BOLD-fMRI联合神经导航显微切除运动区海绵状血管畸形  

BOLD-f MRI combined with neuro-navigation microsurgical removal of cavernous vascular malformations

作　　者：刘进[1] 王伟明[1] 邱伟文 叶碎林[1] LIU Jin;WANG Weiming;QIU Weiwen;YE Suilin(Department of Neurosurgery, Lishui People＇s Hospital in Zhejiang Province, Lishui 323000, Chin)

机构地区：[1]浙江省丽水市人民医院神经外科,浙江丽水323000

出　　处：《中国现代医生》2018年第9期49-52,共4页China Modern Doctor

基　　金：浙江省丽水市公益性技术应用研究项目(2013JYZB49;2011JYZB01);浙江省医药卫生科技计划项目(2010KYB134);浙江省科技厅项目(2017C37111)

摘　　要：目的探讨BOLD-f MRI结合神经导航辅助技术对显微切除运动功能区海绵状血管畸形手术中神经功能保护的价值。方法将41例海绵状血管畸形患者分为导航组(20例)和对照组(21例),导航组予BOLD-f MRI结合神经导航辅助下显微手术治疗,对照组行常规海绵状血管畸形切除术。对比两组患者术前与术后3个月的KPS评分改变及术后并发症发生率。结果术前导航组与对照组KPS评分差异无统计学意义(P>0.05);术后3个月导航组KPS评分高于对照组(P<0.05);导航组术后3个月KPS评分与术前比较明显改善(P<0.05)。结论 BOLDf MRI结合神经导航辅助技术在显微切除运动功能区海绵状血管畸形手术中具有保护神经功能的作用。Objective To investigate the value of BOLD-f MRI combined with neuro-navigational aids in neurofunctional protection during microsurgical removal of motor function cavernous vascular malformation. Methods A total of41 patients with cavernous vascular malformations were divided into the navigation group（n=20） and the control group（n=21）. The navigation group was given BOLD-f MRI combined with neuronavigation-assisted microsurgery. The control group was given conventional cavernous malformation resection. The changes of KPS score and the incidence of postoperative complications between the two groups before surgery and 3 months after the surgery were compared. Results There was no statistically significant difference in KPS score between the navigation group and the control group before surgery（P〉0.05）. The score of KPS in navigation group was higher than that in the control group 3 months after surgery（P〈0.05）; the score of KPS in the navigation group 3 months after the surgery was significantly higher than that before surgery（P〈0.05）. Conclusion BOLD-f MRI combined with neuro-navigational aids can protect neurological function during microsurgical removal of motor function cavernous vascular malformation.

关 键 词：血氧水平依赖性功能磁共振成像 皮层运动区 神经导航 脑海绵状血管畸形 

分 类 号：R739.41[医药卫生—肿瘤]