Hedgehog信号通道与乳腺癌侵袭转移的研究进展  

Research Progress of the Relationship Between Hedgehog Pathway and Angiogenesis in Breast Cancer

作　　者：叶泉英[1] 罗嘉惠 王文希 陈杨杨 李文杰 刘靖[1] 刘娜[1] YE Quan-ying;LUO Jia-hui;WANG Wen-xi(Foshan University, Foshan, Guangdong, 528000, Chin)

机构地区：[1]佛山科学技术学院,广东佛山528000

出　　处：《黑龙江医学》2018年第2期188-189,192,共3页Heilongjiang Medical Journal

基　　金：2015-2016年度佛山科学技术学院校级大学生创新创业训练项目(XJ2016189);佛山市医学类科技攻关项目(2014AB00259)

摘　　要：本文对Hedgehog信号通路的组成与信号转导、Hedgehog信号通路与上皮间质化、Hedgehog信号通路与基质金属蛋白酶、Hedgehog信号通路与肿瘤相关巨噬细胞等Hedgehog信号通路促进乳腺癌侵袭转移涉及的可能机制方面的研究进展进行综述。Epithelial-mesenchymal transition,Matrix metalloproteinases and tumor-associated macrophages are the possible mechanisms involved. From this aspect,the research progress of Hedgehog pathway and invasion of breast cancer is reviewed.

关 键 词：HEDGEHOG信号通路 乳腺癌 侵袭 

分 类 号：R737.9[医药卫生—肿瘤]