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作 者:陈心足[1] 胡建昆[1] CHEN Xinzu;HU Jiankun(Department of Gastrointestinal Surgery / Laboratory of Gastric Cancer, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China)
机构地区:[1]四川大学华西医院胃肠外科/胃癌研究室,成都610041
出 处:《华西医学》2018年第4期379-384,共6页West China Medical Journal
基 金:国家自然科学基金(81301867);四川省青年科技创新研究团队专项计划(2015TD0009);四川大学华西医院学科卓越发展1.3.5工程(ZY2017304);吴阶平医学基金会临床科研专项资助基金(320.2710.1815)
摘 要:胃癌诊疗是一项系统性的多学科协作医疗任务。新模式、新技术、新方案、新药物一直在推陈出新,探索胃癌治疗的最佳策略,以提高胃癌患者的生存结局。该文就精准分期分型为导向的治疗策略、手术质量控制、围手术期新辅助-辅助治疗的合理应用、分子分型与精准治疗4个方面的研究进展和指南更新进行了解读,目的是进一步推广胃癌规范化诊疗和强化其重要性。从知识更新,到意识转变,再到质量提高,降低我国胃癌诊疗质量的异质性,增强指南和共识的依从性,是当前持续深化胃癌规范化诊疗任务的重要内容之一。The diagnosis and treatment of gastric cancer is a systematic and frameworking medical task in a multidisciplinary manner. New models, new technologies, new regimens, and new drugs have been developed to explore the best strategies to improve the survival of patients with gastric cancer. Here we discussed the research progress and guideline updates in four aspects, including the accurate staging-classification-based treatment strategy, the quality control in the surgery, the rational perioperative neoadjuvant-adjuvant therapies, and molecular classification joint with precision medicine. The purpose is to further promote the standardized gastric cancer management in China and emphasize its importance. From the updates of knowledge and the transformation of understanding and recognition, to the quality improvement, it's critical to reduce the heterogeneity of the quality of gastric cancer management in China, as well as enhance adherence to guidelines and consensuses.
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