精准医学在乳腺癌腋窝手术范围的研究进展——降低术后上肢乳腺癌相关淋巴水肿  

Advances in precision medicine in the extent of axillary lymph node surgery of breast cancer: to reduce the postoperative breast cancer-related lymphedema in upper limb

作　　者：刘亚[1] 汪静[1] LIU Ya;WANG Jing(Department of Breast Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China)

机构地区：[1]四川大学华西医院乳腺外科,成都610041

出　　处：《华西医学》2018年第4期459-462,共4页West China Medical Journal

基　　金：四川省科技厅支撑项目(0040205301c24)

摘　　要：乳腺癌是女性最常见的恶性肿瘤之一,乳腺癌发生转移最常见的途径为腋窝淋巴结转移,因此浸润性乳腺癌手术治疗应包括乳房手术以及腋窝手术。但实施乳腺癌腋窝手术后患侧上肢乳腺癌相关淋巴水肿(breast cancer-related lymphedema,BCRL)是术后最常见的中长期并发症,乳腺癌腋窝手术对引流上肢淋巴系统的破坏是造成术后上肢BCRL的主要因素。因此,乳腺癌腋窝手术时精准的腋窝清扫范围对预防BCRL的发生十分重要,可以改善患者的生活质量。该文将围绕乳腺癌手术时对腋窝淋巴结清扫范围的发展作一综述。Breast cancer is one of the most common malignant tumors among women. Typically, the operation of breast cancer should include breast surgery and axillary lymph node surgery since breast cancer first metastasizes to regional axillary lymph nodes. However, postoperative breast cancer-related lymphedema （BCRL） in upper limb is the most common long-term complication. The injury to upper limb lymphatic system contributes to causing the postoperative BCRL. Therefore, precision medicine in the extent of axillary lymph node surgery plays an important role in preventing BCRL which can improve the quality of life in breast cancer patients.

关 键 词：乳腺癌 淋巴水肿 腋窝手术范围 精准医学 综述 

分 类 号：R737.9[医药卫生—肿瘤]