皮瓣点式缝合联合万特普安防治乳腺癌术后皮下积液疗效观察  

Efficacy of Pseudomonas Aeruginosa Preparation(PAP) Combined with Flap Point Suturing in Reducing Seroma Formation After Breast Cancer Surgery

作　　者：喻满成 王伟 范威[1] 许娟[1] 吴新红[1] 冯尧军[1] YU Mancheng;WANG Wei;FAN Wei;XU Juan;WU Xinhong;FENG Yaojun(Department of Breast Cancer, Hubei Cancer Hospital, Wuhan 430079, Chin)

机构地区：[1]湖北省肿瘤医院乳腺科,武汉430079

出　　处：《肿瘤防治研究》2018年第3期163-166,共4页Cancer Research on Prevention and Treatment

摘　　要：目的探讨皮瓣点式缝合联合万特普安防治乳腺癌术后皮下积液的有效性和安全性。方法回顾性分析2015年3月—2017年3月收治的236例乳腺癌手术患者临床资料,依据是否使用万特普安分为两组,术中使用了万特普安的为试验组104例,另一组为对照组132例。比较两组术后总引流量、留管天数、术后皮下积液发生率、皮下积液量、发热率及并发症等。结果试验组总引流量(486.78±32.54)ml少于对照组(502.56±40.12)ml(P=0.001),试验组留管天数、术后皮下积液发生率及皮下积液量均明显少于对照组(均P<0.05),而试验组并没有明显增加发热率及术后并发症发生率(P>0.05)。结论在乳腺癌常规术后皮瓣点式缝合基础上,局部使用万特普安可明显减少术后皮下积液的产生,促进伤口愈合,不良反应少。Objective To evaluate the efficacy and safety of pseudomonas aeruginosa preparation（PAP） combined with flap point suturing in reducing seroma formation after breast cancer surgery. Methods We retrospectively analyzed the clinical data of 236 patients after breast cancer resection in our department from March 2015 to March 2017. According to whether pseudomonas aeruginosa preparation was used or not, the patients were divided into two groups： the experimental group（PAP group, n=104） and the control group（n=132）. The volume of drainage, the duration of drainage, the incidence of seroma formation, the volume of seroma, the rates of heating and the rates of complications were compared. Results The experimental group had a lower drainage volume than the control group（486.78±32.54 ml vs. 502.56±40.12 ml, P=0.001）; the experimental group showed less days of drainage, lower incidence of seroma formation and less volume of seroma（P〈0.05）, however, PAP did not increase the rates of heating or complications（P〈0.05）. Conclusion Basis on flap point suturing, the local use of PAP is a feasible and safe option for reducing or preventing seroma formation and promoting wound healing.

关 键 词：铜绿假单胞菌注射液 皮瓣点式缝合 乳腺癌 皮下积液 

分 类 号：R737.9[医药卫生—肿瘤]