机构地区:[1]佛山爱尔眼科医院屈光中心,佛山528000 [2]北京大学第三医院眼科,100191
出 处:《中华眼科医学杂志(电子版)》2018年第1期23-29,共7页Chinese Journal of Ophthalmologic Medicine(Electronic Edition)
基 金:首都临床特色应用研究专项特色项目(A72502-03);广东省佛山市卫生和计生局医学科研课题(2015335)
摘 要:目的探究不同年龄近视人群角膜水平直径及眼轴长度的变化。方法选取2015年8月至2017年8月于佛山爱尔眼科医院就诊的近视眼患者270例(497只眼)作为研究对象,按照年龄划分为三组,分别是7~17岁组、18~28岁组及29~39岁组,每组90例;采用散瞳验光测量等效球镜的方法检测三组患者的近视程度,按照近视程度再次进行分组,分组标准为低度近视≤-3.00 D;中度近视-3.25^-6.00 D;高度近视>-6.00 D。采用Pentacam眼前节分析系统测量患者的角膜水平直径,采用IOL master光学相干生物测量仪测量患者的眼轴长度。角膜水平直径和眼轴长度采用均数±标准差(x珋±s)进行描述,不同年龄组之间的比较采用方差分析,当差异有统计学意义时,进一步两两比较。结果在低度近视眼患者中,三组患者的角膜水平直径分别是(12.01±0.41)mm、(11.70±0.36)mm和(11.62±0.42)mm。其中,7~17岁组与18~28岁组之间的差异有统计学意义(t=2.64,P<0.05);7~17岁组与29~39岁组之间的差异有统计学意义(t=3.67,P<0.05);但18~28岁组与29~39岁组之间的差异无统计学意义(t=1.29,P>0.05)。三组患者的眼轴长度分别为(24.63±0.61)mm、(24.53±0.80)mm和(24.53±0.93)mm。组间比较,差异无统计学意义(t=0.77,0.65,-0.05;P>0.05)。中度近视眼患者中,三组患者的角膜水平直径分别是(11.89±0.39)mm、(11.71±0.33)mm和(11.63±0.37)mm。其中,7~17岁组与18~28岁组之间的差异有统计学意义(t=2.64,P<0.05);7~17岁组与29~39岁组之间的差异有统计学意义(t=3.67,P<0.05);但18~28岁组与29~39岁组之间的差异无统计学意义(t=1.29,P>0.05)。三组患者的眼轴长度分别是(25.12±0.75)mm、(25.17±0.85)mm和(25.23±0.73)mm。组间比较,差异无统计学意义(t=-0.33,-0.78,-0.39;P>0.05)。高度近视眼患者中,三组患者的角膜水平直径分别是(11.82±0.34)mm、(11.72±0.36)mm和(11.39±0.40)mm。其中,7~17岁组与29~39岁组之间的差异有统计学意义(t=5.95,P<0.05Objective To explore the changes of corneal diameter and ocular axis in different age groups of myopia.Methods 270 cases( 497 eyes) of myopia were selected from August 2015 to August2017 in Foshan ALR ophthalmology hospital.According to the age is divided into three groups,respectively is 7 ~ 17 years old group,18 ~ 28 years group and 29 ~ 39 years group,90 cases in each group; the cycloplegic refraction spherical equivalent measurement of the degree of myopia was detected in three patients,according to the degree of myopia re grouping,grouping criteria for low myopia than-3.00 D,were moderate;-3.25 ~-6.00 D,-6.00 D for high myopia myopia; The corneal diameter of the patients was measured by Pentacam,and the axial length of the patients was measured by IOL master.The length and diameter of axis( x± s) in the form of description,compared with analysis of variance between different age groups,the difference was statistically significant when compared further 22.Results Low myopia,three groups of patients with horizontal corneal diameter were( 12.01±0.41) mm,( 11.70±0.36) mm and( 11.62±0.42) mm,among them,there were statistically significant differences between 7 ~ 17 years group and 18 ~28 years group( t = 2.64,P〈0.05); there was significant difference between 7 ~ 17 years group and 29 ~39 years group( t = 3.67,P〈0.05),but there was no significant difference between 18 ~ 28 years group and29 ~ 39 years group( t = 1.29,P〈0.05).The axial length of the three groups were( 24.63 ± 0.61) mm,( 24.53±0.80) mm and( 24.53±0.93) mm,respectively.There was no significant difference between the two groups( t = 0.77,0.65,-0.05; P〈0.05).Moderate myopia,three groups of patients with horizontal corneal diameter were( 11.89± 0.39) mm,( 11.71 ± 0.33) mm and( 11.63 ± 0.37) mm,among them,there were statistically significant differences between 7 ~ 17 years group and 18 ~ 28 years group( t = 2.64,P〈0.05);there was significant diffe
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