氨基酸离子液体催化合成乳酸乙酯乙酸酯  

Catalytic Synthesis of Ethyl Acetolactate in Amino Acid Ionic Liquids

作　　者：姜小英 张敏[1,2] 史慧珍 杜慧凤 肖毅 黄红梅[1] JIANG Xiao-ying;ZHANG Min;SHI Hui-zhen;DU Hui-feng;XIAO Yi;HUANG Hong-mei(Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research, Ministry of Education;National ＆ Local Joint Engineering Laboratory for New Petro-Chemical Materials and Fine Utilization of Resources, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China)

机构地区：[1]湖南师范大学化学化工学院化学生物学及中药分析教育部重点实验室,中国长沙410081 [2]湖南师范大学化学化工学院石化新材料与资源精细利用国家地方联合工程实验室,中国长沙410081

出　　处：《湖南师范大学自然科学学报》2018年第2期53-57,共5页Journal of Natural Science of Hunan Normal University

基　　金：国家自然科学基金资助项目(21475042);湖南省自然科学基金资助项目(2016JJ4060)

摘　　要：利用置换法合成系列咪唑基氨基酸离子液体,并对其进行FT-IR和1H-NMR表征,考察新型氨基酸离子液体催化剂在乳酸乙酯乙酰化制备乳酸乙酯乙酸酯中的催化作用.结果表明,以氨基酸离子液体[C4mim][Ala]为催化剂,当n(乳酸乙酯)∶n([C4mim][Ala])∶n(乙酸酐)=1∶0.05∶1.2时,于110℃反应6 h,乳酸乙酯转化率及乳酸乙酯乙酸酯选择性分别可达99.8%和99.6%.且[C4mim][Ala]催化剂可重复使用.In this work,a series of imidazolium-based amino acid ionic liquid（ AAIL） catalysts were synthesized by the displacement method and characterized by FT-IR and1 H-NMR techniques. The catalytic effect of novel amino acid ionic liquids on the efficient acetylation of ethyl lactate to ethyl acetolactate was investigated. Our results showed that 99. 8% conversion of substrate and 99. 6% selectivity for ethyl acetolactate could be achieved using AAIL [C4 mim][Ala] as the catalyst under the optimum reaction conditions, i. e., n（ ethyl lactate） ∶n（ [C4 mim][Ala]） ∶ n（ acetic anhydride） = 1 ∶ 0. 05 ∶ 1. 2,T = 110 ℃,and t = 6 h. In addition,the[C4 mim][Ala] catalyst exhibited good reusability.

关 键 词：乳酸乙酯 乙酰化 氨基酸离子液体 乳酸乙酯乙酸酯 催化 

分 类 号：TQ032[化学工程]