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作 者:王相明[1] 张月辉[1] 邵国富[2] Wang Xiangming;Zhang Yuehui;Shao Guofu(Department of Neurology, Central Hospital of Panzhihua , Sichuan Province, Panzhihua 617023, China;Department of Neurology, the 2nd Affiliated Hospital of Soochow University, Suzhou 215004, China)
机构地区:[1]四川省攀枝花市中心医院神经内科,617023 [2]苏州大学附属第二医院神经内科,215004
出 处:《神经疾病与精神卫生》2018年第1期28-31,共4页Journal of Neuroscience and Mental Health
基 金:攀枝花市科技计划项目(2014CY-S-19-9)
摘 要:目的探讨偏头痛患者生活质量的影响因素,为优化偏头痛患者管理提供帮助。方法选择攀枝花市中心医院门诊临床确诊的138例偏头痛患者,完成偏头痛特异性生活质量问卷(MSQ2.1)调查,并记录患者年龄、性别、频率、头痛程度、体重指数(BMI)、广泛性焦虑量表(GAD-7)评分、病人健康问卷抑郁量表(PHQ-9)评分、阿森斯失眠量表(AIS)评分及是否药物滥用、是否先兆性头痛。先进行单因素分析,再以有关联的因素为自变量,MSQ2.1评分为因变量,进行多元线性回归分析。结果单因素分析显示,是否药物滥用、疼痛程度评分、BMI、频率、PHQ-9评分、GAD-7评分、AIS评分与MSQ2.1评分有关(P〈0.05)。多因素分析显示,PHQ-9、GAD-7、AIS评分未进入回归方程(P〉0.05),是否药物滥用,疼痛程度评分、BMI、频率与MSQ2.1评分独立相关(P〈0.05)。结论偏头痛患者滥用止痛药、发作时头痛越重、发作越频繁、BMI越高者,其生活质量越差。Objective To explore the factors affecting quality of life of the migraine patients,and help to optimize the management of the migraine patients.Methods A total of 138 migraine patients in the outpatient clinic of Central Hospital of Panzhihua were recruited and investigated with Migraine Specific Quality of Life Questionnaire 2.1(MSQ 2.1),recording age,gender,frequency(number of headache attacking in a month),degree of headache,body mass index(BMI),the score of Generalized Anxiety Disorder-7 scale(GAD-7),the score of Patient Health Questionnaire 9-item Depression Scale(PHQ-9),the score of Athens Insomnia Scale(AIS),and whether they had substance abuse or precursor headache.Univariate analysis was first applied,and then multivariate linear regression analysis was carried out with the related factors as independent variables and MSQ 2.1 score as dependent variable.Results Univariate analysis showed that MSQ 2.1 score was associated with whether substance abuse,degree of headache,BMI,frequency,PHQ-9 score,GAD-7 score and AIS score(P 〈 0.05).Multiple factor analysis showed that PHQ-9 score,GAD-7 score and AIS score did not enter the regression equation(P 〈 0.05).MSQ 2.1 score was negatively correlated with whether substance abuse,degree of headache,BMI and frequency(P 〈 0.05).Conclusions The abuse of painkillers in migraine patients induce heavier headache,more frequent attacks and higher BMI,which makes the quality of life worse in patients.
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