联合头颈部CTA与全脑CT灌注成像在慢性脑缺血患者中的应用价值  

Application value of the combination use of head-neck CTA and whole brain CT perfusion imaging in patients with chronic cerebral ischemia

作　　者：潘俊[1] 周海[3] 张滨[1] 乔淑冬[2] 杜汉军[2] 张源芳 李澍锴[1] 李新华[1] 哈婷婷 常天静 Pan Jun;Zhou Hai;Zhang Bin;Qiao Shudong;Du Hanjun;Zhang Yuanfang;Li Shukai;Li Xinhua;Ha Tingting;Chang Tianjing(Radiology Department, Peking University Shougang Hospital, Beijing 100144, China;Neurology Department, Peking University Shougang Hospital, Beijing 100144, Chin;Radiology Department, Beijing Tian Tan Hospital, Capital Medical University, Beijing 100050, Chin;Radiology Department, Beijing Rehabilitation Hospital of Capital Medical University, Beijing 100144, China)

机构地区：[1]北京大学首钢医院影像科,100144 [2]北京大学首钢医院神经内科,100144 [3]首都医科大学附属北京天坛医院放射科,100050 [4]首都医科大学附属北京康复医院影像科,100144

出　　处：《神经疾病与精神卫生》2018年第1期37-41,F0003,共6页Journal of Neuroscience and Mental Health

摘　　要：目的通过对慢性脑缺血患者头颈部CTA与全脑CT灌注（CTP）的相关性对比研究，评估两种检查方法在慢性脑缺血患者中的应用价值。方法对150例患者行头颈CTA和全脑CTP检查，对灌注区域分布规律、责任血管与灌注异常区域的关系进行相关对比研究。结果98．72％灌注异常区域其责任血管均为中度以上狭窄。随着责任血管狭窄程度的加重，灌注异常区域比例呈明显递增改变。责任血管狭窄程度与CTP梗死前期分期呈中等正相关。结论结合头颈部CTA与全脑CTP的结果，能全面评判慢性脑缺血患者脑组织的慢性缺血程度，更有利于临床上的相关治疗方法的选择。Objective To estimate the application value of head-neck CT angiography（CTA）and whole brain CT perfusion（CTP）in patients with chronic cerebral ischemia by the correlation comparison study of head-neck CTA and brain CTP.Methods A total of 150 patients＇ CTA and CTP were analyzed for their correlations with the distribution of perfusion region,responsible blood vessels and perfusion abnormalities.Results The responsible vessels of 98.72% perfusion abnormal region were moderate vascular stenosis.With the aggravation of the degree of the stenosis of the responsible vessels,the proportion of abnormal region of perfusion was significantly increased.The degree of responsible vascular stenosis was moderately positively correlated with the staging of CTP in the pre-infarction stage.Conclusions Combined with the results of head-neck CTA and whole brain CTP,the degree of chronic ischemia in patients with chronic cerebral ischemia can be comprehensively evaluated,which is more conductive to the selection of clinical treatment.

关 键 词：慢性脑缺血 头颈部CTA 全脑CT灌注成像 

分 类 号：R743.33[医药卫生—神经病学与精神病学]