量子点表面分子印迹复合荧光探针的研究进展  

Research Advances of Composite Fluorescent Probes Based on Molecularly Imprinted Polymers Coated Quantum Dots

作　　者：卢巧云 毛欣彤 杨星 李孟晔 刘佳 魏芳弟[1] 胡琴[1] LU Qiao-yun;MAO Xin-tong;YANG Xing;LI Meng-ye;LIU Jia;WEI Fang-di;HU Qin(School of Pharmacy Nanjing Medical University ,Nanjing 211166)

机构地区：[1]南京医科大学药学院,江苏南京211166

出　　处：《分析科学学报》2018年第2期281-286,共6页Journal of Analytical Science

基　　金：国家自然科学基金(No.81173016);江苏省高等学校大学生创新创业训练计划(No.201510312040Y)

摘　　要：分子印迹是一种制备对目标化合物具有高选择性的高分子聚合物材料的技术。制备的分子印迹聚合物(MIPs)因含有与模板分子在空间结构和功能基团排布上高度吻合的三维空穴,从而对模板分子具有良好的记忆效应。在量子点(QDs)表面印迹MIPs层,可制备QDs@MIPs复合材料,该复合材料兼具QDs荧光检测的高灵敏度和MIPs的高选择性,在生物、药物和环境分析等领域受到越来越多的关注。本文就QDs@MIPs的合成及应用的研究进展进行了综述。Molecular imprinting is a promising strategy to design tailor-made materials with high selectivity for a target molecule. The resulting molecularly imprinted polymers（MIPs） showed a higher affinity for the template molecule than for other structurally related compounds. Composite materials with characteristics of high selectivity and sensitivity were constructed by anchoring MIPs on the surface of QDs（QDs@MIPs）,and have attracted much attention in the fields of bioanalysis, pharmaceutical and environmental analysis.

关 键 词：量子点 分子印迹聚合物 荧光探针 

分 类 号：O657.39[理学—分析化学]