脐尿管癌的临床诊疗及预后分析  

Clinical management and progonsis analysis of urachal carcinoma

作　　者：晋连超[1] 杨冰[1] 潘东亮[1] 舒芳敏 周哲[1] 李宁忱[1] JIN Lian-chao;YANG Bing;PAN Dong-liang;SHU Fang-min;ZHOU Zhe;LI Ning-chen(Department of Urinary Surgery, Peking University Shougang Hospital, Beijing 100144, China)

机构地区：[1]北京大学首钢医院泌尿外科,北京100144

出　　处：《中国肿瘤临床与康复》2018年第4期427-429,共3页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的探讨脐尿管癌的临床诊断和治疗方法。方法选取2008年10月至2016年10月间北京大学首钢医院收治的9例脐尿管癌患者,均行手术治疗,其中行扩大膀胱部分切除术7例,行根治性膀胱切除术2例。术后均给予奥沙利铂+亚叶酸钙+氟尿嘧啶(FOLFOX4方案)化疗4~6个周期。7例患者术后采用三维适形放疗。结果患者术后腺癌8例,移行细胞癌1例。术后复发转移的中位时间为15个月,中位生存时间为22个月。结论脐尿管癌恶性程度高,早期诊断较困难,预后差,诊断应结合临床表现、影像学和病理检查,治疗以手术为主。Objective To elucidate and assess the management strategies of urachal carcinoma including its diagnosis and treatment. Methods Clinical data of 9 patients with urachal carcinoma were reviewed retrospectively at Peking University Shougang Hospital from October 2008 to October 2016. All patients underwent surgery. Seven patients underwent extensive partial cystectomy,and 2 patients underwent radical cystectomy. After surgery,they were given oxaliplatin plus calcium folinate and fluorouracil（ FOLFOX4） chemotherapy for 4 to 6 cycles. After surgery,7 patients received three-dimensional conformal radiotherapy. Results Postoperative pathology confirmed adenocarcinoma in 8 patients and transitional-cell carcinoma in 1 patient. The median recurrence and metastasis time was 15 months,and median survival time was 22 months. Conclusion Urachal carcinoma is a highly malignant cancer that is difficult to diagnose early. The diagnosis of urachal carcinoma requires combination of clinical manifestations,imaging and pathological manifestations,and surgical resection is the main treatment.

关 键 词：脐尿管肿瘤 诊断 治疗 生存 

分 类 号：R737.1[医药卫生—肿瘤]