80例人乳头瘤病毒HPV分型阳性检测结果分析  

Analysis of positive resμlts of human papillomavirus HPV typing in 80 cases

作　　者：凤婷 陈徳林 金长碧 刘雁[1] Feng Ting;Chen Delin;Jin Changbi;Liu Yan(Department of Laboratory, First People＇s Hospital, Zunyi, Guizhou, 563000, Chin)

机构地区：[1]遵义市第一人民医院检验科,贵州遵义563000

出　　处：《当代医学》2018年第14期100-102,共3页Contemporary Medicine

摘　　要：目的研究人乳头瘤病毒核酸检测HPV阳性分型结果与子宫病变的关系,了解病核酸检测分型结果与病变种类的临床意义。方法采用信号引物转移定性聚合酶链反应测定子宫肿瘤、子宫平滑肌瘤、子宫炎症患者宫颈分泌物中HPV分型结果,用全自动SLAN-96P核酸检测仪进行核酸阴阳性分析。结果子宫肿瘤36例定性检出阳性率主要16型为38.9%、52型阳性为27.8%、58型阳性为22.2%、39型阳性为8.3%、82型阳性为8.3%、68型阳性为5.6%。子宫平滑肌瘤23例检出阳性率主要16型为21.7%、52型阳性为17.4%、58型阳性为13.0%、82型阳性为13.0%、39型阳性为8.7%、68型阳性为8.7%。子宫炎症21例定性检出阳性率主要52型阳性为28.6%、58型阳性为23.8%、59型阳性为19.0%、16型为14.3%、18型阳性为9.5%、68型阳性为9.5%、35型阳性为9.5%。各组间差异有统计学意义(P<0.05)。结论研究人乳头瘤病毒感染核酸检测HPV阳性分型结果:子宫肿瘤主要是16型、52型和58型感染为主。子宫平滑肌瘤主要是16型、52型和58型感染为主。子宫炎症主要52型、58型、59型和16型感染为主。Objective To study the relationship between HPV positive typing results and uterine lesions in human papilloma virus nucleic acid test, and to understand the clinical significance of the classification results and types of disease nucleic acid detection. Methods The primers signal transfer qualitative polymerase chain reaction assay uterine tumor, uterine fibroids, inflammation in patients with uterine cervical secretions of HPV types as a result, use automatic SLAN - 96 p nucleic acid detector for masculine nucleic acid analysis. Results In 36 cases of uterus tumor, the posi- tive rate was 38.9%, 52 positive was 27.8%, 58-type positive was 22.2%, type 39 was 8.3%, and type 82 was 8.3%. The type 68 positive was 5.6%. In the 23 cases of uterine leiomyoma, the positive rate was 21.7%, type 52 positive was 17.4%, type 58 positive was 13.0%, type 82 positive was 13.0%, type 39 was 8.7%, and the positive was 8.7%. In the 21 cases of uterine inflammation, the positive rate of positive rate was 28.6%, 58-type positive was 23.8%, 59-type positive was 19.0%, type 16 was 14.3%, and type 18 was 9.5%. The type 68 positive was 9.5% and 35 positive was 9.5%. The differences among the groups were statistically significant （P〈0.05）. Conclusion HPV positive genotypes were detected by human papil- lomavirus infection. The uterine tumors were mainly 16, 52 and 58. Uterine leiomyoma mainly consists of 16, 52 and 58 infections. There were mainly 52, 58, 59 and 16 infections in uterine inflammation.

关 键 词：人乳头瘤病毒 子宫病变 核酸检测HPV阳性分型 

分 类 号：R737.33[医药卫生—肿瘤]