急性脑梗死患者颈动脉粥样硬化斑块与胱抑素C及载脂蛋白B水平的关系  

Relationship between carotid atherosclerosis plaque and levels of serum Cystatin C and Apolipoprotein B in patients with acute cerebral infarction

作　　者：于翔[1] 温慧军 YU Xiang;WEN Huijun.(Department of Neurology, Baoji Municipal Central Hospital, Baoji 721008, China)

机构地区：[1]陕西省宝鸡市中心医院,陕西宝鸡721008

出　　处：《中风与神经疾病杂志》2018年第4期317-319,共3页Journal of Apoplexy and Nervous Diseases

摘　　要：目的探讨急性脑梗死患者颈动脉粥样硬化斑块与胱抑素C(Cystatin C Cys-C)及载脂蛋白B(Apolipoprotein B ApoB)的关系。方法 112例急性脑梗死患者经颈动脉超声检查分为无斑块组(32例)、稳定斑块组(38例)及不稳定斑块组(42例);检测各组患者血清Cys-C及ApoB水平,并进行组间比较。结果稳定斑块组及不稳定斑块组血清Cys-C及ApoB水平明显高于无斑块组(均P<0.05);不稳定斑块组高于稳定斑块组(均P<0.05)。且随着斑块程度的增加,其血清Cys-C及ApoB水平也明显增高(均P<0.05)。结论血清Cys-C及ApoB水平可以反映急性脑梗死患者颈动脉粥样硬化的严重程度,值得临床推广应用。Objective To explore the relationship between carotid atherosclerosis plaque and levels of serum Cystatin C and Apolipoprotein B in patients with acute cerebral infarction（ ACI）. Methods One hundred and twelve ACI patients were divided into non plaque group（ 32 cases）,stable plaque group（ 38 cases） and unstable plaque group（ 42 cases）. The levels of serum Cystatin C and Apolipoprotein B were detected,and the results were compared among these groups. Results The levels of serum Cystatin C and Apolipoprotein B in stable plaque group and unstable plaque group were significantly higher than those in non plaque group（ all P〈0. 05）; and which in unstable plaque group were higher than those in stable plaque group（ all P〈0. 05）. With the increase of plaque,the levels of serum Cystatin C and Apolipoprotein B were increased accordingly（ all P〈0. 05）. Conclusion The levels of serum Cystatin C and Apolipoprotein B are related to the severity of carotid atherosclerosis in ACI patients,that is worthy of clinical application and dissemination.

关 键 词：急性脑梗死 颈动脉粥样硬化 胱抑素C 载脂蛋白B 

分 类 号：R743.3[医药卫生—神经病学与精神病学]