双重染色内镜应用于消化道早癌的诊断价值  

Diagnostic value of double staining endoscopy in early digestive tract cancer

作　　者：汪望月[1] 叶洁桐[1] 叶国良[2] WANG Wang-yue;YE Jie-tong;YE Guo-liang(Department of Digestive of Lishui People＇ s Hospital, Lishui, Zhejiang 323000, Chin)

机构地区：[1]丽水市人民医院消化科,浙江丽水323000 [2]宁波大学医学院附属医院消化内科,浙江宁波315020

出　　处：《中华全科医学》2018年第5期768-770,共3页Chinese Journal of General Practice

基　　金：2017年度浙江省省级公益技术应用研究和软科学研究计划项目(2017C35004)

摘　　要：目的通过分组对比,探讨消化道早癌诊断中双重染色内镜的应用价值。方法选取2015年5月—2017年6月接受胃肠镜检查的患者752例,根据不同检查方法对患者实施分组,对照组490例行常规内镜检查,发现可疑病灶予以活检,观察组262例行内镜下双重染色检查,对2组患者结直肠黏膜、胃黏膜、食道黏膜病变及早癌检出情况予以对比,采用SPSS 19.0统计软件对数据进行处理。结果观察组结直肠黏膜病变共检出57例,检出率为80.28%,对照组结直肠黏膜病变共检出37例,检出率为25.52%,2组差异有统计学意义(P<0.05);观察组结直肠早癌检出率为5.63%,对照组未检出结直肠早癌,2组差异有统计学意义(P<0.05);观察组胃黏膜病变共检出56例,检出率为64.37%,对照组胃黏膜病变共检出24例,检出率为14.81%,2组差异有统计学意义(P<0.05);观察组胃早癌检出率为4.60%,对照组未检出胃早癌,2组差异有统计学意义(P<0.05);观察组食管黏膜病变共检出19例,检出率为18.27%,对照组食管黏膜病变共检出8例,检出率为4.37%,2组差异有统计学意义(P<0.05);观察组食管早癌检出率为3.85%,对照组未检出食管早癌,2组差异有统计学意义(P<0.05)。结论双重染色内镜可显著提高消化道早癌检出率,为疾病诊断及治疗方案制定提供有效指导,值得推广。Objective The application value of double staining endoscopy in the diagnosis of early digestive tract cancer by grouping comparison. Methods Total 752 cases of gastrointestinal endoscopy patients were selected from May, 2015 to June, 2017, and divided into groups according to different examination methods. The control group （490 cases） re- ceived routine endoscopic examination, suspicious lesions were detected by biopsy, and the observation group （262 ca- ses） underwent double staining under endoscopy, two groups of patients with colorectal mucosa, gastric mucosa, esopha- geal mucosal lesions, early detection of cancer were compared. Data processing with SPSS 19.0 software. Results A to- tal of 57 cases of colorectal lesions were detected in the observation group, the detection rate was 80.28%, 37 cases of colorectal mucosa lesions were detected in the control group, the detection rate was 25.52% , the difference between the two groups was statistically significant （P 〈 0.05 ） ; The detection rate of colorectal early cancer was 5.63% , and no ear- ly colorectal cancer was found in the control group. The difference between the two groups was statistically significant （P 〈 0.05） ; A total of 55 cases of gastric mucosal lesions were detected in the observation group, the detection rate was 64.37%, and 24 cases of gastric mucosal lesions in the control group were detected, the detection rate was 14.81%, the difference between the two groups was statistically significant （P 〈 0.05） ; The detection rate of early gastric cancer was 4.60% , and the early gastric cancer was not detected in the control group. The difference between the two groups was statistically significant （P 〈0.05 ）; A total of 19 cases of esophageal mucosa lesions were detected in the observation group, the detection rate was 18.27%, and 8 cases of esophageal mucosal lesions in the control group were detected, the detection rate was 4.37%, the difference between the two groups was statistically significant （P 〈0.05

关 键 词：消化道 早癌诊断 内镜检查 双重染色 

分 类 号：R730.49[医药卫生—肿瘤] R735[医药卫生—临床医学]