脑梗死患者血常规检测结果与颈动脉病变程度相关性分析  

Related Analysis on Routine Blood Tests Results and Carotid Artery Lesions Degree in Patients with Cerebral Infarction

作　　者：朱玲[1] 吴琳娜[1] 伍晓梅 李凤[1] Zhu Ling;Wu Linna;Wu Xiaomei;Li Feng(West China Hospital,Sichuan University,Chengdu 610041,China)

机构地区：[1]四川大学华西医院,四川成都610041

出　　处：《北华大学学报（自然科学版）》2018年第3期358-361,共4页Journal of Beihua University（Natural Science）

基　　金：四川省卫生和计划生育委员会科研基金项目(14003261)

摘　　要：目的探讨脑梗死患者血常规检测结果与颈动脉病变程度的关系.方法体检中心120例脑梗死患者为脑梗死组,70例体检正常的志愿者为健康对照组,比较两组血常规指标,包括白细胞计数(WBC)、红细胞计数(RBC)、红细胞压积(HCT)、平均红细胞体积(MCV)、红细胞分布宽度(RDW)、平均血小板体积(MPV)、血小板分布宽度(PDW)、血小板计数(PLT),同时应用彩色多普勒超声检测其颈动脉内中膜厚度(intimal-medial wall thickness,IMT),根据IMT厚度分为正常、内膜增厚、斑块形成3组,评估4组血常规指标变化情况.结果 IMT内膜增厚56例,斑块形成64例,其中不稳定斑块34例,稳定斑块30例;健康对照组各血常规指标与脑梗死组比较差异均具有统计学意义(P<0.05);且脑梗死组MCV为(83.61±5.27)f L,显著低于健康对照组((85.83±6.91)f L),WBC,RBC,HCT,MPV,RDW及PLT均显著高于健康对照组(P<0.05);内膜增厚组与斑块组WBC,MCV差异无统计学意义(P>0.05),但RBC,HCT,MPV,RDW,PLT均显著低于斑块组(P<0.05);稳定斑块组WBC,HCT,MCV,RDW指标与不稳定斑块组比较差异均无统计学意义(P>0.05),但RBC,MPV,PLT均显著高于不稳定斑块组(P<0.05).结论脑梗死患者血细胞及血小板相关参数可发生改变,对脑梗死患者展开血常规检测有助于判断疾病的发生与发展,为临床治疗提供参考.Objective To explore the relationship between the blood routine test results and the carotid artery lesions degree in patients with cerebral infarction. Method 120 cases of patients diagnosed as cerebral infarction in the physical examination center were collected in the cerebral infarction group,and 70 volunteers with normal physical examination were selected as the healthy control group. The blood routine indexes,including white blood cell count（ WBC）,red blood cell count（ RBC）,hematocrit（ HCT）,mean corpuscular volume（ MCV）,red cell distribution width（ RDW）,mean platelet volume（ MPV）,platelet distribution width（ PDW）,platelet count（ PLT） were compared between the two groups. Color Doppler ultrasound was used to detect the carotid artery intima-media wall thickness（ IMT）. According to IMT,the patients were divided into the normal group,the intimal thickening group and the plaque formation group,and the blood routine indexes changes were assessed among the four groups. Results There were 56 cases of IMT intimal thickening and 64 cases of plaqueformation（ 34 cases of unstable plaque and 30 cases of stable plaque）. There were significant differences in the blood routine indexes between the healthy control group and the cerebral infarction group（ P0. 05）. The MCV level in the cerebral infarction group was significantly lower than that in the healthy control group（（ 83. 61 ±5. 27） f L vs（ 85. 83 ±6. 91） f L）,and the levels of WBC,RBC,HCT,MPV,RDW and PLT were significantly higher than those in the healthy control group（ P0. 05）. There were no significant differences in the levels of WBC and MCV between the intimal thickening group and the plaque group（ P0. 05）,but the levels of RBC,HCT,MPV,RDW and PLT in the former group were significantly lower than those in the plaque group（ P0. 05）. The levels of WBC,HCT,MCV and RDW indexes in the stable plaque group were not significantly different from those in the unstable plaque group（ P0. 05）,but the lev

关 键 词：脑梗死 脂糖代谢 血清尿酸 炎性因子 颈动脉粥样硬化 

分 类 号：R743[医药卫生—神经病学与精神病学]