缺血性脑卒中患者眼底病变分析  

Characteristics of fundus florescence angiography in patients with cerebral ischemic stroke

作　　者：朱敏[1] 李国培[1] 陈玉冰[1] 雷玉[1] 陈燎原[1] 温友红[1] Zhu Min;Li Guopei;Chen Yubing;Lei Yu;Chen Liaoyuan;Wen Youhong(Department of Ophthalmology, Foshan Firsit People＇s Hospital,Foshan, Guangdong 528000,China)

机构地区：[1]广东省佛山市第一人民医院眼科,528000

出　　处：《临床眼科杂志》2018年第2期154-156,共3页Journal of Clinical Ophthalmology

摘　　要：目的观察缺血性脑卒中患者的眼底改变,分析伴有不同心脑血管疾病危险因素的脑卒中患者眼底改变的差异。方法使用荧光素眼底血管造影检查观察伴有不同心脑血管疾病危险因素的缺血性脑卒中患者的眼底改变。主要危险因素包括高血压、糖尿病、高脂血症和吸烟史等4项。患者被分为5组。对照组由70例不伴有上述危险因素的脑卒中患者组成。A组由69例仅患糖尿病的脑卒中患者组成。B组由71例仅伴有高血压的脑卒中患者构成,C组由72例同时伴有高血压、糖尿病及高脂血症但没有吸烟史的脑卒中患者构成。D组由65例同时患有上述4项危险因素的脑卒中患者构成。出现1种眼底病变计1分,使用SPSS10.0进行统计分析,P<0.05被认为差异有显著性。结果对照组与其他各组的眼底病变计分均有显著统计学差异。A组与B组的眼底病变计分无显著统计学差异。C组与D组眼底病变计分无显著统计学差异。A组与C组以及A组与D组的眼底病变计分均有显著统计学差异。结论对于缺血性脑卒中患者,糖尿病与高血压对眼底改变的总体影响可能无明显差异;而对于同时患有高血压、糖尿病及高脂血症的缺血性脑卒中患者,吸烟可能并没有明显增加视网膜结构的异常改变。Objective To examine the characteristics of retinal changes in patients with cerebral ischemic stroke. Methods The fundus florescence angiography（ FFA） was obtained from patients with ischemic stroke and various risk factors,including hypertension,hyperlipidemia,diabetes mellitus,and history of smoking. Patients were recruited for each risk factor. Normal subjects were enrolled as control. Patients get 1 point for each retinal change. Data were analyzed in SPSS 10. 0. Results Risk score was significantly different between control subjects and stroke patients. The score was also significantly different between stroke patients with diabetes and stroke patients with hypertension,diabetes and hyperlipidemia,and stroke patients with all 4 risk factors. Conclusions For ischemic stroke patients,hypertension or diabetes alone may not manifest in FFA. If the patient had hypertension,diabetes and hyperlipidemia,smoking history may not affect the FFA characteristics.

关 键 词：缺血性脑卒中 眼底病变 视功能 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R773.4[医药卫生—临床医学]