荧光分光光度法测定斯达舒中铝的含量  

Determination of Aluminum in Si Dashu by Fluorescence Spectrophotometry

作　　者：王堃 陈瑾 赵春晓 郭爱玲 WANG Kun;CHEN Jin;ZHAO Chunxiao;GUO Ailing(School of Chinese Materia Medica, Shanxi University of Chinese Medicine, Jinzhong 030619, China)

机构地区：[1]山西中医药大学中药学院,山西晋中030619

出　　处：《中国民族民间医药》2018年第8期34-36,共3页Chinese Journal of Ethnomedicine and Ethnopharmacy

基　　金：山西中医药大学博士科研启动基金项目(2014)

摘　　要：目的:建立测定斯达舒中铝含量的新方法。方法:以萘甲醛席夫碱为络合剂,采用荧光分光光度法,在醋酸铵-醋酸(p H=7)的缓冲溶液中测定斯达舒中铝的含量。结果:在激发波长为437 nm,发射波长为525 nm处,用荧光分光光度法对浓度0~6μmol/L范围内铝离子标准溶液进行荧光强度的测定,结果表明荧光强度和浓度具有较好的线性关系,平均加样回收率为99.02%~102.03%,准确度较好。结论:该方法选择性好、灵敏度高、响应时间短、操作简便,适合于胃药斯达舒中铝含量的测定。Objective To establish a new method for the determination of aluminium in Si Dashu. Method The content of alumi- num in Si Dashu was determined in ethanoic acid -ammonium acetate cushion fluid （ pH = 7 ） with naphthalene formaldehyde Schiff base as complexing agent by fluorescence spectrophotometry. Result The calibration curve of aluminum ion with good linearity was ob- tained over the range of 0 -6 μmol/L at the excitation wavelength of 437 nm and the emission wavelength of 525 nm. The recovery rate was 99. 02% -102. 03% with good accuracy. Conclusion The method has the advantages of high sensitivity, selectivity, short re- sponse time and simple operation. The method was suitable for determining the aluminum content in Si Dashu.

关 键 词：铝 荧光分光光度法 斯达舒 

分 类 号：R914.1[医药卫生—药物化学]