新生儿非癫痫发作性异常运动  

Paroxysmal non-epileptic motor phenomena in newborns

作　　者：刘露 程国强 Liu Lu;Cheng Guoqiang(Key Laboratory of Neonatal Disease, Ministry of Health, Children＇ s Hospital of Fudan University, Shanghai 201102, China)

机构地区：[1]卫生部新生儿疾病重点实验室复旦大学附属儿科医院新生儿科,上海201102

出　　处：《国际儿科学杂志》2018年第4期278-281,共4页International Journal of Pediatrics

基　　金：上海市科学技术委员会基金（16411953400）

摘　　要：新生儿易出现各种发作性异常运动，包括生理性（中枢神经系统发育不成熟）、病理性（癫痫和非癫痫），临床医生应对各种原因引起的发作性异常运动现象进行正确的鉴别诊断。某些特定的临床特征可以帮助医生鉴别生理性、病理性，癫痫、非癫痫发作性异常运动，而视频脑电图（video electroencephalo—gram，VEEG）是鉴别癫痫和非癫痫发作性异常运动的金标准，有助于进一步明确新生儿发作性异常运动现象的病因。该文主要综述新生儿常见的非癫痫性发作性异常运动现象的临床特征、病理生理机制和鉴别诊断要点。A variety of paroxysmal motor phenomena often occur in newborns,including physiological events（ immaturity of the central nervous system） and pathological events（ epileptic and non-epileptic）. The clini- cian should be able to properly identify and diagnose the paroxysmal motor phenomena with various etiologies. There are some clinical features that may help clinicians with the differentiation among physiological and patho- logical, epileptic and non-epileptic events. However, VEEG monitoring is still the gold standard for differentiating the paroxysmal motor phenomena of epileptic and non-epileptic seizures, which can help to further clarify the eti- ology. In this paper, the clinical features, underlying pathophysiological mechanisms and differential diagnoses of non-epileptic paroxysmal motors in newborns were reviewed.

关 键 词：新生儿 非癫痫发作 震颤 肌阵挛 张力失调 

分 类 号：R748[医药卫生—神经病学与精神病学]