Like mother, like daughter： heritability of female Richardson＇s ground squirrel Urocitellus richardsonii cortisol stress responses  

作　　者：Kevin R. BAIROS-NOVAK Calen R RYAN Angela R. FREEMAN W. Gary ANDERSON James F, HARE 

机构地区：[1]Department of Biological Sciences, University of Manitoba, Winnipeg, Manitoba, R3T 2N2, Canada [2]Departmentof Biology, University of Saskatchewan, Saskatoon, S7N 5E2 Saskatchewan, Canada [3]Department ofAnthropology, Northwestern University, Evanston, 60208 Illinois, USA [4]Department of Biological Sciences,Kent State University, Kent, 44242 Ohio, USA

出　　处：《Current Zoology》2018年第2期153-163,共11页动物学报（英文版）

摘　　要：Activation of the hypothalamic-pituitary-adrenal （HPA） axis liberates glucocorticoids, which provides an acute indication of an individual＇s response to stressors. The heritability of the stress response in wild mammals, however, remains poorly documented. We quantified the cortisol stress response of female Richardson＇s ground squirrels （RGSs） to handling and physical restraint, testing for： （1） the effects of individual age, time of day, and sample latency; （2） repeatability within individuals; （3） narrow-sense heritability; and （4） differences among individuals owing to potential genetic and/or environmental effects. We detected a positive linear relationship between baseline plasma cortisol （BL-cortisol） concentration and stress-induced plasma cortisol （Sl-cortisol） concentration that defined each individual＇s cortisol stress response. BL-cortisol, SI-cortisol, and stress response did not differ according to the time the sample was taken, or by subject age. Cortisol stress response was highly repeatable within individuals, had a mother-offspring heritability of h2 =0.40 ± 0.24 （mean ±SE）, full-sibling heritability of h2s = 0.37 ± 0.71, and half-sibling heritabil- ity of hHS^2 = 0.75 ± 1.41. Stress responses of sibling groups, immediate-family groups, and squir- rels within a given area did not differ, whereas those of individuals from more distantly related matrilines did. Our results highlight the natural variability in HPA axis reactivity among individuals by quantifying both BL- and SI-cortisol levels, demonstrate partial heritability of the stress response that is not attributable to environmental variation, and suggest that at least part of an indi- vidual＇s stress response can be accounted for by differences in matrilineal history.

关 键 词：GLUCOCORTICOIDS ground squirrel HERITABILITY hypothalamic-pituitary-adrenal axis reactivity stress response. 

分 类 号：Q959.837[生物学—动物学] S852.32[农业科学—基础兽医学]