非甾体类抗炎药相关性消化性溃疡出血的临床分析  

Clinical characteristics of non-steroidal anti-inflammatory drugs induced peptic ulcer bleeding

作　　者：冯建峰 赵青山 FENG Jian？feng;ZHAO Qingshan(Department of Gastroenterology,People′s Hospital of Taishan City,Taishan 529200,Chin)

机构地区：[1]台山市人民医院消化科,广东台山529200

出　　处：《实用医学杂志》2018年第9期1513-1515,共3页The Journal of Practical Medicine

摘　　要：目的探讨非甾体类抗炎药(NSAIDs)相关性消化溃疡出血的临床特点。方法通过临床对照研究,比较142例NSAIDs相关性溃疡出血与210例非NSAIDs相关性溃疡出血的临床资料。结果 NSAIDs组患者在年龄、性别、伴随风湿免疫性疾病或心脑血管疾病、溃疡部位和数目、腹痛症状、血红蛋白浓度、住院时间等方面与非NSAIDs组比较,差异具有统计学意义(P<0.05),两组在溃疡大小、尿素氮、HP感染方面比较,差异无统计学意义。结论应采取适宜的措施降低NSAID相关性消化性溃疡出血的并发症。Objective To study the clinical characteristics of non-steroidal anti-inflammatory drugs（NSAIDs）induced peptic ulcer bleeding（PUB）. Methods The case-control study was used to analyze the clinicaldata of 142 patients with NSAIDs-induced PUB and 210 patients with non-NSAIDs-induced PUB. Results Therewere significant differences between the two groups regarding sex and age of patient,history of rheumatic diseases orcardio-cerebral-vascular disease,types and numbers of ulcer,abdominal pain,hemoglobin concentration,andhospital stay（P〈0.05）,but there was no obvious difference in terms of the size of ulcer,BUN and HP infectionrate. Conclusion Proper measures should be employed to decrease the complications of NSAIDs-induced PUB.

关 键 词：非甾体类抗炎药 消化溃疡出血 胃镜表现 临床特点 

分 类 号：R573.1[医药卫生—消化系统]