首发延髓梗死不同卒中解剖模式与TOAST病因分型的临床分析  

Clinical analysis of different apoplexy patterns of first onset medulla infarction and TOAST etiological classification

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作  者:张鹏[1] 牛莉莉[1] 肖成华 耿德勤 王炎强[3] 胡屹伟[1] Zhang Peng , Niu Lili , Xiao Chenghua , Geng Deqin, Wang Yanqiang , Hu Yiwei(1.Department of Neurology, Zaozhuang Municipal Hospital of Shandong, Zaozhuang 277102, China; 2.Department of Neurology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, China; 3.Department of Neurology, the Affiliated Hospital of Weifang Medical University, Weifang 261031, Chin)

机构地区:[1]山东省枣庄市立医院神经内科,277102 [2]徐州医科大学附属医院神经内科,221002 [3]潍坊医学院附属医院神经内科,261031

出  处:《中国实用医刊》2018年第8期4-7,共4页Chinese Journal of Practical Medicine

基  金:山东省中医药科技发展计划项目(2017-223);徐州医科大学博士后启动基金(2015107026);山东省医药卫生科技发展计划项目(2015WS0051)

摘  要:目的探讨首发延髓梗死不同卒中解剖模式与TOAST病因分型的临床特点。方法回顾性分析103例首发延髓梗死患者的临床资料,包括性别、年龄、危险因素、卒中模式、梗死部位分布及影像学结果等。延髓梗死病因分型依据TOAST标准,卒中解剖模式根据弥散加权成像(DWI)的影像学表现及供应动脉分布范围分为前内侧、前外侧、外侧、后部梗死,据延髓解剖特点轴位分为上部、中部、下部梗死。结果共纳入103例延髓梗死患者,其中男76例(73.77%),女27例(26.21%);高血压60例(58.25%),糖尿病42例(40.78%),高同型半胱氨酸血症37例(35.92%),吸烟36例(34.95%),高脂血症33例(32.04%)。梗死部位:延髓上部41例(39.80%),中部32例(31.18%),下部18例(17.85%),中上部6例(5.82%),中下部4例(3.88%),全部延髓21例(1.94%)。病因分型:大动脉粥样硬化型(LAA)63例(61.17%),小动脉闭塞型(SAO)14例(13.59%),心源性栓塞型(CE)6例,其他明确病因型(ODE)8例,不明原因型(SUE)12例。受累血管以椎动脉为主(56例,54.37%)。结论延髓梗死的卒中解剖模式及病因分型与其动脉供血区域不同有关,为临床诊治干预及预后评估提供了依据。Objective To evaluate the clinical characteristics of different apoplexy patterns of first onset medullary infarction and TOAST etiological classification. Methods Retrospectively analyzed the clinical data of 103 patients with primary medullary infarction, including gender, age, risk factors, stroke patterns, distribution of infarct sites, and imaging results. The etiological classification of medul- lary infarction was based on the TOAST standard, the apoplexy pattern was divided into medial, antero- lateral, lateral and posterior infarcts based on the imaging findings of diffusion weighted imaging (DWI) and the distribution of arterial distribution, the axial position of the medulla was divided into upper, mid- die and lower infarcts. Results A total of 103 patients with medullary infarction were enrolled, there were 76 males (73.77%) and 27 females (26. 21% ). Common risk factors: hypertension in 60 cases (58.25%) , diabetes in 42 cases (40. 78% ), smoking in 36 cases (34.95%) , homoeysteinemia in 37 cases (35.92%) , hyperlipidemia in 33 cases (32.04%). Infarct site: the upper part of medulla oblon- gata of 41 cases (39.80%) , middle of 32 cases (31.18%) , lower part of 18 cases (17.85%) , middle and upper part of 6 cases (5.82%) , middle and lower part of 4 cases (3.88%) , all medulla of 2 cases ( 1.94% ). The pathogeny: 63 cases (61.17%) of large atherosclerosis (LAA), 14 cases ( 13.59% ) of arteriole occlusion (SAO), 6 cases of cardiogenic embolism (CE), 8 cases of other clear etiological type (ODE), 12 cases of stroke of undetermined etiology (SUE). The main blood vessels were vertebral artery (56 cases, 54. 37% ). Conclusions The apoplexy pattern and etiological classification of the me- dullary infarction are correlated with the different arterial blood supply regions, and provide the basis for the intervention and prognosis evaluation of the clinical diagnosis and treatment.

关 键 词:延髓梗死 解剖模式 危险因素 TOAST分型 病因分型 

分 类 号:R743.3[医药卫生—神经病学与精神病学]

 

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