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作 者:何伟[1] 秦如斋[1] 张小冬[1] 刘文丹[1] HE Wei;QIN Ru - zhai;ZHANG Xiao - dong;LIU Wen - dan(Oncology Department of The Fourth Affiliated Hospital of C, uangzhou Medial University, Guangzhou 511447, China)
出 处:《微量元素与健康研究》2018年第3期13-14,共2页Studies of Trace Elements and Health
基 金:广东省医学科研基金资助课题(编号:A2015375)
摘 要:目的:研究消化道恶性肿瘤患者红细胞分布宽度(RDW)的特点,探讨其与预后的关系。方法:分析近3年收治的142例消化道肿瘤患者RDW-CV值的特点,研究其与贫血严重度、肿瘤TNM分期、患者Karnofsky评分以及低蛋白血症之间的关系。结果:伴有贫血的消化道恶性肿瘤患者的RDW-CV值明显高于无贫血患者,且与贫血程度呈正相关,肿瘤分期为Ⅲ+Ⅳ期或伴有低蛋白血症患者的RDW-CV值明显高于Ⅰ+Ⅱ期或血清白蛋白水平正常的患者,而RDW-CV值与患者的KPS评分无关。结论:消化道恶性肿瘤患者的RDW-CV值与患者的贫血程度、肿瘤TNM分期以及是否伴有低蛋白血症有关,可间接预测患者的预后。Objective: To study the RDW(red blood cell distribution width) and explore its correlation with the clinical prognosis for patients with malignant gastrointestinal tumor. Method: The RDW-CV value for 142 cases with malignant gastrointestinal tumor was reviewed. The correlation of RDW with the patient's anemia degree,TNM staging,Karnofsky points and hypoproteinemia was analyzed.Result: The RDW-CV value for malignant gastrointestinal tumor patients complicated with anemia was significantly higher than patients without anemia. The RDW-CV value had a positive correlation with the anemia degree. The RDW-CV value for Ⅲ + Ⅳ stage of tumor patients or complicated patients with hypoproteinemia was significantly higher than Ⅰ + Ⅱ stage of tumor patients or normal ALB patients. The RDW-CV value had no correlation with the patient's KPS points. Conclusion: For patients with malignant gastrointestinal tumor,the RDW-CV value is correlated with the patient's anemia degree,TNM staging and complications of hypoproteinemia.Therefore,it can make an indirect prediction in the patient's prognosis.
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