血小板与肿瘤转移关系的研究进展  

Progress of relationship between platelets and tumor metastasis

作　　者：程玉强[1,2] 张修平 李楠[1] 程树群[1] Cheng Yuqiang;Zhang Xiuping;Li Nan;Cheng Shuqun(Department of Hepatic Surgery 6, Eastern Hepatobiliary Surgery Hospital, the Second Military Medical University, Shanghai 200433, Chin;Department of General Surgery, the 234th Hospital of PLA, Chaoyang 122000, China)

机构地区：[1]第二军医大学附属东方肝胆外科医院肝外六科,上海200433 [2]解放军第二三四医院普外科,辽宁朝阳122000

出　　处：《肿瘤研究与临床》2018年第4期278-281,共4页Cancer Research and Clinic

基　　金：国家重点基础研究发展计划（973计划）（2015CB554005）;国家杰出青年科学基金（81125018）;教育部长江学者计划（2013）;国家创新研究群体科学基金（81221061）;国家自然科学基金（81472282）

摘　　要：转移是恶性肿瘤的主要特征之一，也是引起预后不良的重要因素，其发生机制较为复杂。越来越多的证据表明，血小板与肿瘤转移密切相关，并在此过程中发挥了关键的作用。血小板计数异常可作为肿瘤预后的参考指标之一，而抗血小板治疗在肿瘤治疗中的作用也更加重要。文章就血小板在肿瘤转移中作用的研究进展作一综述。As the key features of tumor, metastasis has multiple mechanisms and could cause poor survival. Accumulated evidences indicate that platelet plays an important role in tumor metastasis. Platelet count had become a significant indicator for predicting tumor prognosis, and antiplatelet therapy is an effective way for tumor treatment. Here, the recent advancements of the relationship between platelets and tumor metastasis are reviewed.

关 键 词：血小板 肿瘤转移 

分 类 号：R730.2[医药卫生—肿瘤]