腹腔镜下根治术与耻骨后开放性手术治疗前列腺癌的临床疗效比较及分析  

Comparison and Analysis of the Clinical Efficacy of Laparoscopic Radical Mastectomy and Post Pubis Open Surgery for the Treatment of Prostate Cancer

作　　者：陈家胜[1] 丁勇泉[1] 李汉强[1] 邓灿[1] 林巧威 CHEN Jiasheng;DING Yongquan;LI Hanqiang;DENG Can;LIN Qiaowei(Gaozhou People＇s Hospital, Gaozhou 525200 Chin)

机构地区：[1]高州市人民医院,广东高州525200

出　　处：《锦州医科大学学报》2018年第2期39-42,共4页Journal of Jinzhou Medical University

基　　金：茂名市科技局课题;项目编号:2015123

摘　　要：目的 分析腹腔镜下前列腺癌根治术相比耻骨后开放性手术的疗效差异,为患者手术方法的具体选择提供理论支持。方法 回顾性分析2010年1月至2016年12月期间,我院收治的126例符合研究要求的前列腺癌确诊患者进行研究。根据患者手术方式分为开放性手术组和腹腔镜手术组,每组均为63例患者。比较两组患者手术指标(手术操作时间、术中平均出血量、术后平均住院时间、导尿管具体留置时间)、临床疗效、术后并发症(尿失禁、尿漏、吻合口狭窄、勃起功能障碍)及1年复发率的统计学差异。结果 两组患者临床手术指标进行比较,腹腔镜手术组患者手术操作时间、平均出血量、住院时间、导尿管留置时间均好于开放性手术组(均有P<0.05);腹腔镜手术组和开放性手术组患者临床疗效的差异有统计学意义(P<0.05),腹腔镜手术组患者临床有效率明显高于开放性手术组;两组患者术后并发症发生率及1年复发率的差异均无统计学意义(均有P>0.05),但是腹腔镜手术组患者并发症及1年复发率普遍低于开放性手术组。结论 腹腔镜下前列腺癌根治术相比耻骨后开放性手术,其临床疗效相对更好,同时有更短的手术时间、手术出血量及住院时间,但术后并发症及随访1年复发率的差异不明显。Objective To analyze the difference between laparoscopic radical prostatectomy and open surgery for posterior pubic symphysis so as to provide theoretical support for specific selection of operative methods.Methods Aretrospective analysis of 126 cases of prostate cancer diagnosed in our hospital from January 2010 to December 2016 was carried out.According to the surgical methods, the patients were divided into open operation group and laparoscopic operation group with 63 patients respectively.The statistical difference of operation index（operation time, average intraoperative bleeding volume, postoperative hospitalization time, catheter specific indwelling time）, clinical efficacy, postoperative complications（ urinary incontinence, urinary leakage, anastomotic stenosis, erectile dysfunction） and 1 year recurrence rate of patients in the two groups were compared.Results The clinical surgical indicators of the two groups were compared, the surgical operation time, the average amount of bleeding, hospitalization time, catheter specific indwelling time of patients in the laparoscopic surgery group were better than those of patients in the open surgery group（ both P0.05）, the difference of clinical curative effect between the laparoscopic group and the open surgery group was statistically significant（P0.05）.The clinical efficiency of patients in the operation group was significantly higher than that of patients in the open surgery group; the postoperative complication rate and the difference of the 1 year recurrence rate of patients in the two groups were not statistically significant（all P0.05）, but the complications and 1 year recurrence rate of patients in the laparoscopic surgery group were generally lower than those of patients in the open surgery group.Conclusion Laparoscopic radical prostatectomy is better than open surgery for posterior pubic symphysis with shorter operative time, less operative bleeding and shorter hospital stay.However,there is no significant difference in postoperative c

关 键 词：腹腔镜 列腺癌根治术 开放性手术 

分 类 号：R737.25[医药卫生—肿瘤]