Gd-EOB-DTPA增强MRI与超声造影对小肝癌诊断价值的对比分析  

Diagnostic value of Gd-EOB-DTPA enhanced MRI compared with contrast-enhanced ultrasound for small hepatocellular carcinoma

作　　者：任涛[1,2] 谢双双 黄黎香[1] 柴超[1] 沈文[1] REN Tao;XIE Shuangshuang;HUANG Lixiang;CHAI Chao;SHEN Wen(Department of Radiology, Tianjin First Central Hospital, Tianjin 300192 ,China;Department of Medical Imaging, Tianjin Huanhu Hospital, Tianjin 300350, China)

机构地区：[1]天津市第一中心医院放射科,天津300192 [2]天津市环湖医院影像科,天津300350

出　　处：《实用放射学杂志》2018年第5期690-693,共4页Journal of Practical Radiology

基　　金：国家自然科学基金项目（81671657）。

摘　　要：目的 对比分析钆塞酸二钠（Gd-EOB-DTPA）增强MRI及超声造影（CEUS）对小肝癌（sHCC）的诊断价值。方法 收集行Gd-EOB-DTPA增强MRI及CEUS检查，且最终病理证实为sHCC患者22例（共29个病灶）。Gd-EOB-DTPA增强MRI诊断sHCC的模式为：T1WI呈等、低信号，T2WI呈稍高或高信号，扩散加权成像（DWI）呈高信号，动脉期明显强化和/或肝胆期廓清；CEUS诊断sHCC的模式为：动脉期快速强化和延迟期呈低回声。结果 Gd-EOB-DTPA增强MRI与CEUS对sHCC诊断的灵敏度分别为82.76%和65.52%，差异无统计学意义（χ2=2.248，P=0.134），特异度均为100%。结论 Gd-EOB-DTPA增强MRI与CEUS对sHCC诊断的灵敏度和特异度均无明显差异，前者的灵敏度更高。Objective To compare the diagnostic value of Oadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid （Gd-EOB-DTPA） enhanced MRI and contrast-enhanced ultrasound （CEUS） in detection of small hepatocellular carcinoma （sHCC）.Methods A total of 22 patients with 29 lesions who underwent Gd-EOB-DTPA enhanced MRI and CEUS scan, and confirmed as sHCCs by pathology were included in this study.Gd-EOB-DTPA enhanced MRI pattern for the conclusive diagnosis of sHCC were lesions showed iso or low signal on T1WI, showed slightly high signal or high signal on T2 WI, showed high signal on DWI and obviously enhanced in the arterial phase and/or clearance in the hepatohiliary phase; CEUS pattern for the conclusive diagnosis of sHCC were rapidly increasing in the arterial phase and showing low echo in the delay phase.Results The diagnostic sensitivity of detecting sHCC by Gd-EOB-DTPA enhanced MRI and CEUS were 82.76% and 65.52 % respectively, and there was no statistical difference (X2 =2.248, P =0.134), the diagnosis specificity were both 100% .Conclusion Both of the diagnostic sensitivity and specificity for detecting sHCC hy Gd-EOB-DTPA enhanced MRI and CEUS showed no difference,the value of diagnostic sensitivity of the former is higher.

关 键 词：小肝癌 钆塞酸二钠 磁共振成像 超声造影 

分 类 号：R735.7[医药卫生—肿瘤] R445.2[医药卫生—临床医学]