氯吡格雷、阿司匹林联合治疗老年短暂性脑缺血发作的效果分析  

Analysis of effect of clopidogrel combined with aspirin in the treatment of transient ischemic attack in the elderly

作　　者：张鹏[1] 牛莉莉[1] ZHANG Peng;NIU Li-li.(Department of Internal Medicine-Neurology, Zaozhuang Municipal Hospital, Zaozhuang 277102, China)

机构地区：[1]枣庄市立医院神经内科,277102

出　　处：《中国实用医药》2018年第13期95-96,共2页China Practical Medicine

摘　　要：目的分析氯吡格雷、阿司匹林联合治疗老年短暂性脑缺血发作的临床效果。方法 78例老年短暂性脑缺血发作患者作为研究对象,根据治疗方法不同分为实验组与对照组,各39例。两组患者入院后均给予临床基础治疗,在此基础上,对照组采用阿司匹林治疗,实验组采用氯吡格雷和阿司匹林联合治疗,观察两组患者临床疗效及不良反应发生情况。结果治疗后,实验组患者总有效率为97.44%,明显高于对照组的84.62%,差异具有统计学意义(P<0.05)。两组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论在老年短暂性脑缺血发作的治疗中,采用氯吡格雷和阿司匹林联合治疗能有有效提升治疗效果,值得临床推广和应用。Objective To analysis the clinical effect of clopidogrel combined with aspirin in the treatment of transient ischemic attack in the elderly. Methods A total of 78 elderly patients with transient ischemic attack as study subjects were divided by different treatment methods into experimental group and control group, with 39 cases in each group. Both groups received clinical basic treatment after admission, on this basis, the control group was treated with aspirin, and the experimental group was treated with clopidogrel combined with aspirin. The clinical efficacy and occurrence of adverse reactions between the two groups was observed. Results After treatment, the experimental group had obviously higher total effective rate as 97.44% than 84.62% in the control group, and the difference was statistically significant（P〈0.05）. Both groups had no statistically significant difference in incidence of adverse reactions（P〉0.05）. Conclusion Combination of clopidogrel and aspirin can effectively improve the treatment effect of elderly patients with transient ischemic attack, and it is worthy of clinical promotion and application.

关 键 词：氯吡格雷 阿司匹林 短暂性脑缺血发作 老年 

分 类 号：R743.31[医药卫生—神经病学与精神病学]