天津市18岁及以上社区人群抑郁症患病率及影响因素  

Morbidity and influencing factors of depression in adult residents of Tianjin

作　　者：王小丽 尹慧芳[2] 徐广明[2] 杨建立[3] 李美娟 黄彦[2] 谢筠[2] WANG Xiao-ii, YIN Hui-fang, XU Guang-ming, YANG Jian-li, LI Mei-juan, HUANG Yah, XIE Jun(Tianjin Medical University, Tianjin 300070, Chin)

机构地区：[1]天津医科大学,天津300070 [2]天津市安定医院 [3]天津医科大学总医院

出　　处：《中国慢性病预防与控制》2018年第4期274-277,共4页Chinese Journal of Prevention and Control of Chronic Diseases

基　　金：天津市卫生行业重点攻关项目(13KG119)

摘　　要：目的调查天津市居民的抑郁症患病情况,分析患病的影响因素,为制定抑郁症的防治策略提供依据。方法数据来源于2011年7-12月实施的天津市精神障碍流行病学调查项目,用多阶段随机整群抽样方法,在天津市城乡社区中抽取15 538名18岁及以上居民,用一般健康问卷(GHQ-12)、基于《精神障碍诊断与统计手册(4版)》(Diagnostic and Statistical Manual of Mental Disorders-IV,DSM-IV)设计的DSM-IV临床定式访谈(the Structured Clinical Interview for DSM,SCID)对抑郁症进行筛查。用SPSS 19.0软件进行统计学分析。不同人群中抑郁症的患病率比较用χ~2检验,用logistic回归分析影响抑郁症患病的相关社会因素。结果天津市抑郁症终身患病率为3.7%,1月时点患病率(以下简称为时点患病率)为1.1%。女性终身患病率、时点患病率(分别为4.9%、1.5%)明显高于男性(分别为2.6%、0.8%),农村居民终身患病率、时点患病率(分别为5.0%、2.0%)明显高于城市居民(分别为3.3%、0.9%),差异均有统计学意义(P<0.05,P<0.01)。55~岁居民抑郁症终身患病率、时点患病率分别为5.7%、2.1%,40~54岁居民分别为3.9%、1.3%,18~39岁居民分别为2.6%、0.6%,随着年龄的增加,终身患病率、时点患病率逐渐升高,差异均有统计学意义(P<0.01)。多因素logistic回归分析显示,男性(OR=0.524,95%CI:0.372~0.738)、未婚(OR=0.278,95%CI:0.124~0.619)、已婚(OR=0.439,95%CI:0.274~0.702)、家庭妇女(OR=0.476,95%CI:0.229~0.990)是抑郁症终身患病的保护因素,生活条件差(OR=1.810,95%CI:1.068~3.065)是抑郁症终身患病的危险因素。生活条件差、中等的居民抑郁症时点患病风险分别是生活条件好的3.248倍(OR=3.248,95%CI:1.052~10.033)、3.507(OR=3.507,95%CI:1.430~8.602)。结论天津市居民抑郁症患病率较高,对于有抑郁症危险因素的人群和抑郁症患者应加强关注,进行精神健康教育,提供良好的社会支持,降低心理应激水平,以达到真正�Objective To investigate the morbidity of depression in adult residents of Tianjin, to analyze the influencing factors and to provide the basis for the prevention and treatment of depression. Methods The data were from the epidemiological investigation program of psychogenia in Tianjin during July to December in 2011. Multistage random cluster sampling was used to select 15 538 adult residents（≥18 years old） as the subjects. The General Health Questionnaire（GHQ-12） and the Structured Clinical Interview for DSM（SCID） designed on the basis of the Diagnostic and Statistical Manual of Mental Disorders-IV（DSM-IV） were used to screen the depression. The used software was SPSS 19.0. The χ-2 test was utilized to anlyzed the differences of depression morbidities between different groups, and logistic regression was used to analyze the related social factors of depression morbidity.Results The lifetime morbidity of depression in Tianjin was 3.7%, and the 1-month morbidity（point morbidity） was 1.1%. The lifetime morbidity（4.9%） and point morbidity（1.5%） of depression in females were significantly higher than those（2.6% and 0.8%） in males; the lifetime morbidity（5.0%） and point morbidity（2.0%） of depression in females were significantly higher than those（3.3% and 0.9%） in males（P〈0.05 or P〈0.01）. The lifetime morbidity and point morbidity of depression in 〉55 years old subgroup were 5.7% and 2.1%,the lifetime morbidity and point morbidity of depression in 40-54 years old subgroup were 3.9%and 1.3%, the lifetime morbidity and point morbidity of depression in 18-39 years old subgroup were 2.6% and 0.6%, the lifetime morbidity and point morbidity of depression increased significantly with age（P〈0.01）. Logistic regression analysis showed that the protective factors of life morbidity of depression were male（OR=0.524, 95%CI： 0.372-0.738）, unmarried（OR=0.278, 95%CI：0.124-0.619）,married（OR =0.439, 95% CI： 0.274-0.702）, housewife（OR =0.476, 95% CI： 0

关 键 词：社区人群 抑郁症 社会因素 

分 类 号：R749.4[医药卫生—神经病学与精神病学]