器械吻合手术联合顺铂治疗食管癌的效果及对患者营养水平的影响  

Effect of instrument anastomosis combined with cisplatin on esophageal cancer and its effect onnutritional level of patients

作　　者：张国庆 Zhang Guoqing(Department of Thoracic Surgery, People＇s Hospital of Houma, Houma 043000, Chin)

机构地区：[1]山西省侯马市人民医院胸外科,043000

出　　处：《中国实用医刊》2018年第9期60-62,共3页Chinese Journal of Practical Medicine

摘　　要：目的探讨器械吻合手术联合顺铂治疗食管癌的效果及对患者营养水平的影响。方法选取食管癌患者60例，随机分为对照组与研究组。对照组28例给予器械吻合手术治疗，研究组32例给予器械吻合手术联合顺铂方案治疗。比较两组根治性手术的切除率及术后并发症发生情况，测定两组治疗前后血清总蛋白、白蛋白含量，比较两种治疗方法对患者营养水平的影响。随访3年，统计比较两组患者的3年生存率。结果研究组根除率（87．50％）高于对照组（71．42％），差异有统计学意义（P〈0．05）；研究组并发症发生率（12．50％）低于对照组（21．43％），差异有统计学意义（P〈0．05）。随访3年，研究组生存率（53．13％）高于对照组（25．00％），差异有统计学意义（P〈0．05）。两组治疗前后血清总蛋白及白蛋白含量比较差异未见统计学意义（P〉0．05）。结论食管癌患者采用器械吻合手术联合顺铂治疗，可提高手术根除率，降低术后并发症发生率，提高术后3年生存率。Objective To investigate the effect of instrument anastomosis combined with eispla-tin on esophageal cancer and the effect on nutritional level of patients. Methods Sixty patients with e-sophageal cancer were selected and randomly divided into control group and study group. Twenty-eight patients in control group were treated by instrument anastomosis, 32 cases in study group were treated by instrument anastomosis operation combined with cisplatin. The resection rate and postoperative complica-tions of radical surgery were compared between the two groups. The content of serum total protein and al-bumin were measured before and after treatment in two groups to compare the effects of the two treatment methods on the nutritional level in patients. After 3 years of follow-up, the survival rates of the 3 years were compared between the two groups. Results The eradication rate of study group （87.50%） was significantly higher than that of control group （71.42%） , and the difference was statistically significant （P 〈0. 05). The incidence of complications in study group （12. 50%) was significantly lower than that in control group （21.43%）, and the difference was statistically significant （P 〈0. 05). After 3 years of follow-up, the survival rate of study group （53.13%） was higher than that of control group （25.00%）, and the difference was statistically significant (P 〈 0. 05). There was no significant difference in serum total protein and albumin in the two groups before and after treatment （P 〉 0. 05). Conclusions Surgi-cal anastomosis combined with cisplatin in the treatment for patients with esophageal cancer can improve the eradication rate, reduce incidence of postoperative complications, and improve the 3-year survival rate. It should be further applied in clinical.

关 键 词：器械吻合手术 顺铂 食管癌 营养水平 

分 类 号：R735.1[医药卫生—肿瘤]