影响视网膜中央静脉阻塞黄斑水肿视力预后的主要因素  

The main effective factors for the visual outcome of macular edema secondary to central retinal vein occlusion

作　　者：薛灿灿 窦宏亮[1] Xue Cancan;Dou Hongliang(Peking University Third Hospital, Peking University Eye Center, Beijing 100191, China)

机构地区：[1]北京大学第三医院北京大学眼科中心,100191

出　　处：《中华眼底病杂志》2018年第3期291-295,共5页Chinese Journal of Ocular Fundus Diseases

摘　　要：视网膜中央静脉阻塞所致的黄斑水肿常导致严重的视力损害.玻璃体腔注射抗血管内皮生长因子、糖皮质激素类药物能有效消退黄斑水肿和改善视力,但其视力预后受多重因素影响.视网膜血流灌注,特别是黄斑区微循环情况与视力预后明显相关,缺血型尤其是黄斑区浅、深层毛细血管网破坏严重的患眼视力预后差.此外,视网膜各层结构的完整性与视力预后密切相关,中心凹下椭圆体带、外界膜完整的患眼视力预后好;基线视力好、治疗早期反应好以及年轻、治疗及时的患眼视力预后较好.Macular edema （ME） secondary to central retinal vein occlusion （CRVO） often cause severe visual impairment. Intravitreal anti-vascular endothelial growth factor agents and steroids can effectively eliminate ME and improve visual function, but the visual outcome is affected by multiple factors. Retinal blood flow, especially the macular microcirculation, has significant correlation with visual outcome. Ischemic CRVO, especially patients with severe damage in the deep and superficial vascular layer of the macular zone, usually have poor visual outcome. In addition, the integrity of the multi-layer retinal structure closely correlates with the visual outcome. Patients with intact ellipsoid zone, external limit membrane beneath the fovea have good visual recovery. Additionally, good baseline visual acuity, positive response to treatment in early phase, young age and timely treatment usually brings about better visual outcome.

关 键 词：视网膜静脉闭塞/并发症 黄斑水肿 视力 预后因素 

分 类 号：R774.1[医药卫生—眼科]