胆源性消化不良患者采取复方阿嗪米特肠溶片治疗的效果分析  

Analysis of effect of compound azintamide enteric-coated tablets in the treatment of patients with biliary dyspepsia

作　　者：嵇秀丽 JI Xiu-li.(Inner Mongolia Hulunbeier People＇ s Hospital, Hulunbeier 021008, China)

机构地区：[1]内蒙古呼伦贝尔市人民医院,021008

出　　处：《中国实用医药》2018年第14期17-19,共3页China Practical Medicine

摘　　要：目的探讨复方阿嗪米特肠溶片治疗胆源性消化不良的临床效果。方法 60例胆源性消化不良患者,按照随机数字法分为对照组和观察组,每组30例。对照组患者采用消炎利胆片治疗,观察组患者采用复方阿嗪米特肠溶片治疗。比较两组患者临床症状改善时间、治疗后胃肠症状评估量表(GSRS)评分以及不良反应发生率。结果观察组患者腹胀、恶心、呕吐症状改善时间分别为(12.32±3.39)、(7.64±1.37)、(7.23±2.36)d均明显短于对照组的(14.28±3.69)、(8.36±1.15)、(8.44±1.54)d,差异具有统计学意义(P<0.05)。治疗后,观察组患者GSRS评分均明显低于对照组,差异具有统计学意义(P<0.05)。观察组患者不良反应发生率为6.67%,明显低于对照组的26.67%,差异具有统计学意义(P<0.05)。结论复方阿嗪米特肠溶片治疗胆源性消化不良效果较好,可有效改善患者临床症状,降低不良反应发生率,提高患者生活质量,值得临床推广应用。Objective To discuss the clinical effect of compound azintamide enteric-coated tablets in the treatment of patients with biliary dyspepsia. Methods A total of 60 patients with biliary dyspepsia were divided by random number table method into control group and observation group, with 30 cases in each group. The control group was treated with inflammation-resolving gall-bladder-excreting tablet, and the observation group was treated with compound azintamide enteric-coated tablets. Comparison were made on clinical symptom improvement time, gastrointestinal symptom rating scale （GSRS） score and incidence of adverse reactions between the two groups. Results The observation group obviously shorter abdominal distension, nausea, vomiting symptoms improvement time as （1Z32 ± 3.39）, （7.64 ± 1.37） and （7.23 ± 2.36） d than （14.28 ± 3.69）, （8.36 ± 1.15） and （8.44 ± 1.54） d in control group, and the difference was statistically significant （P〈0.05）. After treatment, the observation group had obviously lower GSRS score than the control group, and the difference was statistically significant （P〈0.05）. After treatment, the observation group had obviously lower incidence of adverser reactions as 6.67% than 26.67% in the control group, and the difference was statistically significant （P〈0.05）. Conclusion Compound azintamide entericcoated tablets shows excellent effect in treating biliary dyspepsia, and it can effectively improve the clinical symptom, reduce incidence of adverse reactions, and improve the quality of life. It is worthy of clinical promotion and application.

关 键 词：复方阿嗪米特肠溶片 胆源性消化不良 消炎利胆片 

分 类 号：R57[医药卫生—消化系统]