口腔干燥综合征中医古代文献述要  

Chinese traditional medicine literature review of oral sjogren syndrome

作　　者：丁洋[1,2] 张声生[1] 韩建民[3] 杜正光[1] 孟梦[1] 张天麒[1] 余芳[1,2] 李柳骥 DING Yang;ZHANG Shengsheng;HAN Jianmin;DU Zhengguang;MENG Meng;ZHANG Tianqi;YU Fang;LI Liuji(Digestion Center, Beijing Hospital of Chinese Medicine Affiliated to the Capital University of Medical Sciences, Beijing 100010, China;Beijing University of Chinese Medicine, Beijing 100029, China;Stomatological Hospital of Peking University, Beijing 100081, China)

机构地区：[1]首都医科大学附属北京中医医院消化中心,北京100010 [2]北京中医药大学,北京100029 [3]北京大学口腔医院,北京100081

出　　处：《吉林中医药》2018年第5期612-616,共5页Jilin Journal of Chinese Medicine

基　　金：国家自然科学基金项目(81400560);北京市自然科学基金项目(7164265)

摘　　要：在当代,口腔干燥综合征发病率日益增高。考察中医古籍,得到以下结论,病名:使用较多、命名较规范的是"口干""口燥"和"口渴",以"口干"为优。病位:涉及心、脾、肺、肾、大肠、胃等,但以心、脾、肺为多。病性:属热,但医藉中或主虚热,或主实热,或主上热下寒。病机:《诸病源候论》认为是腑脏虚热、津液亏虚以及阴阳断隔、上热下寒;《圣济总录》则认为是心经蕴热、传之于脾以及热积上焦、口舌失润;后世又补充了脾胃气虚、血虚、血瘀、水停等病机。治法与处方:晋代《葛氏方》中首载治口干方,创口含剂型;南北朝谢士泰《删繁方》开始标本兼治;自《备急千金要方》起清热生津法成为后世治疗口干的普遍之选;《圣济总录》在古代医籍中载治口干方最多,剂型最为丰富。In contemporary era, the incidence oforal sjogrenhas been rising. By investigating the ancient TCMtraditional Chinese medicineclassics, the authors drew the following conclusions： name of disease： the frequently used and relatively standard names of oral sjogren in TCM classics were ＂kougan＂, ＂kouzao＂ and ＂kouke＂. According to our study, ＂kougan＂ wasthe best one. Location of disease： the recorded locations of oral sjogren in ancient literature involved heart, spleen, lung, kidney, large intestine, stomach, etc. However, the heart, spleen and lung were intended to be mentioned more frequently according to relevant prescriptions. Nature of disease： in ancient literature, the disease nature of sjogren ascribed to heat with no final conclusion of being deficiency-heat, excess-heat or upper heat and lower cold. Mechanism of disease： in Treatise on the Origins and Manifestations of Various Diseases（Zhu Bing Yuan Hou Lun）, the mechanism of xerostomia was believed to be deficiency heat in viscera and bowels, fluid depletion, yin-yang separation and upper heat with lower cold. Comprehensive Recording of Divine Assistance（Sheng Ji Zong Lu） took the theory of heat transmission from heart channel to spleen channel and dry mouth due to upper jiao heat as the main mechanism. Doctors in later generations complemented other mechanisms such as spleen-stomach qi deficiency, blood deficiency, blood stasis and water retention. Therapeutic methods and prescriptions： Prescription for dry mouth was first mentioned in Ge＇s formulas（Ge Shi Fang） in Jin dynasty, which was the very first oral tablet of edible and medicinal materials. Shan Fan Formulas（Shan Fan Fang） by XIE Shitai in Northern and Southern dynasties initiated the method to treat the root and branch simultaneously. Important Formulas Worth a Thousand Gold Pieces for Emergency（Bei Ji Qian Jin Yao Fang） set the precedent of clearing heat and promoting fluid production, which became a common practice in later generations. Compreh

关 键 词：口腔干燥综合征 口干 治法 文献研究 

分 类 号：R221[医药卫生—中医基础理论]