不同大小甲状腺乳头状癌常规超声及超声造影特征的比较  

Comparison of the characteristics of the conventional ultrasound and contrast-enhanced ultrasound in papillary thyroid carcinoma of different sizes

作　　者：樊文文[1] 刘利平[1] 张炎晶[1] 王潇婧 刘静静[1] FAN Wen-wen, LIU Li-ping, ZHANG Yan-jing, WANG Xiao-jing, LIU Jing-jing(Department of Ultrasound,the First Hospital of Shanxi Medical University,Taiyuan 030001,Chin)

机构地区：[1]山西医科大学第一医院超声科,山西太原030001

出　　处：《中国当代医药》2018年第13期4-7,共4页China Modern Medicine

基　　金：人社部留学回国人员科技活动择优资助项目(2016-366);山西省回国留学人员科研资助项目(2014-073)

摘　　要：目的探讨不同大小甲状腺乳头状癌的常规超声及超声造影特征。方法回顾性分析我院2016年1月~2017年9月经手术病理证实的197例(239个)甲状腺乳头状癌的超声表现,依据结节大小分为甲状腺微小乳头状癌(PTMC组)与>1 cm的乳头状癌(非PTMC组),对比研究两组的常规超声与超声造影特征。结果 PTMC组128个,非PTMC组111个。PTMC组纵横比(A/T)>1较非PTMC组明显多(64.8%vs.15.3%),微钙化较非PTMC组少(61.7%vs.82.9%),差异有统计学意义(均P<0.05);PTMC组超声造影不均匀增强、向心性增强较非PTMC组少(59.4%vs.79.3%,37.5%vs.51.4%),差异有统计学意义(均P<0.05)。两组在回声、边缘、增强程度方面差异均无统计学意义(均P>0.05)。结论不同大小甲状腺乳头状癌超声特征有所差异。A/T>1在微小癌中明显多见,对PTMC有更好的诊断价值。随着癌结节的增大,较大癌结节微钙化、超声造影不均匀增强、向心性增强更多见。Objective To investigate the characteristics of the conventional ultrasound and contrast-enhanced ultrasound（CEUS） in papillary thyroid carcinoma of different sizes.Methods The ultrasonographic features of 197 cases（239 nodules） of papillary thyroid carcinoma which were confirmed by surgical pathology in our hospital from January 2016 to September 2017 were analyzed retrospectively.These papillary thyroid carcinomas were divided into papillary thyroid micro-carcinoma（PTMC） and papillary thyroid carcinoma（non-PTMC） which size greater than 1 cm according to the nodule′s size,and the conventional ultrasound and the CEUS characteristics of them were comparatively studied.Results There were 128 cases of PTMC and 111 cases of non-PTMC.The A/T1 in PTMC group was more obvious than that in non-PTMC group（64.8% vs. 15.3%）,the micro-calcification in PTMC were less than that in non-PTMC（61.7% vs.82.9%）,which showed significant difference between the two groups（all P0.05）.Compared with non-PTMC,heterogeneous enhancement and centripetal enhancement of PTMC was less（59.4% vs. 79.3%,37.5% vs. 51.4%）,and significant difference were founded（all P0.05）.No significant difference were founded in echo,margin and the enhancement intensity between two groups（all P 0.05）.Conclusion In different sizes′ papillary thyroid carcinoma,the ultrasonographic characteristics are different.The A/T1 is much more common in micro-carcinoma,which is helpful for detecting PTMC.With the size greater,the incidence of micro-calcification,heterogeneous enhancement and centripetal enhancement is much more.

关 键 词：甲状腺乳头状癌 甲状腺微小乳头状癌 常规超声 超声造影 

分 类 号：R736.1[医药卫生—肿瘤]