幽门螺杆菌感染的危害和防控  

Harm of Helicobacter pylori infection and its prevention and control

作　　者：王芬[1] 刘文忠[2] Wang Fen;Liu Wenzhong(Department of Gastroenterology, Third Xiangya Hospital of Central South University, Changsha 410013, Hunan, China;Department of Gastroenterology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China)

机构地区：[1]中南大学湘雅三医院消化科,湖南长沙410013 [2]上海交通大学医学院附属仁济医院消化科,上海200127

出　　处：《疾病监测》2018年第4期276-281,共6页Disease Surveillance

摘　　要：幽门螺杆菌(HP)感染是人类最常见的慢性感染之一,目前我国人群中的HP感染率仍高达40%~50%。HP感染者几乎均会发生慢性活动性胃炎,部分感染者可发生消化性溃疡、消化不良,少数感染者可发展至胃癌,HP感染是胃部疾病的罪魁祸首。此外,HP感染与不明原因缺铁性贫血、特发性血小板减少性紫癜等胃外疾病的发病密切相关。根除HP对HP感染相关疾病的治疗和预防起重要作用。HP感染可通过口-口、粪-口和胃-口途径在人-人之间传播;HP主要在家庭内传播;改变不良卫生习惯可减少其传播。Helicobacter pylori infection is one of the most common chronic infections in humans. At present,the rate ofH. pylori infection in Chinese population ranges from 40% to 50%. The persons infected with H. pylori almost all have chronicactive gastritis. Peptic ulcers and dyspepsia might develop in some infected persons,and gastric cancer might develop in smallnumber of the infected persons. Therefore,H. pylori infection is a major cause of stomach diseases. In addition,H. pyloriinfection is also closely related to the pathogenesis of some extragastric diseases,such as unexplained iron deficiency anemia andidiopathic thrombocytopenic purpura. The eradication of H. pylori plays an important role in the treatment and prevention of therelated diseases. H. pylori infection can be transmitted from person to person through oral-oral,fecal-oral and stomach-oralroutes;H. pylori is mainly transmitted in families. Promoting healthy habits can facilitate the reduction of H. pylori transmission.

关 键 词：幽门螺杆菌 慢性活动性胃炎 消化性溃疡 胃癌 治疗 预防 

分 类 号：R573.6[医药卫生—消化系统]