垂体促甲状腺激素腺瘤的诊治  

Experience in the diagnosis and treatment of thyroid-stimulating hormone-secreting pituitary adenoma

作　　者：张建宇[1] 刘福增[2] 关健 Jianyu Zhang;Fuzeng Liu;Jian Guan(Department of Tumor, the 251st Hospital of PLA, Zhangjiakou 075000, China;Department of Neurosurgery, the 251st Hospital of PLA, Zhangjiakou 075000, China;Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China)

机构地区：[1]中国人民解放军第二五一医院肿瘤科,河北省张家口市075000 [2]中国人民解放军第二五一医院神经外科 [3]中国医学科学院北京协和医院神经外科垂体腺瘤外科治疗中心

出　　处：《中国肿瘤临床》2018年第10期513-516,共4页Chinese Journal of Clinical Oncology

摘　　要：目的:分析垂体促甲状腺激素(thyroid stimulating hormone,TSH)腺瘤的临床特点和诊治经验。方法:总结2006年1月至2014年2月于中国人民解放军第二五一医院诊治的14例垂体TSH瘤的诊断、治疗过程及预后。结果:14例患者中,2例直接接受手术治疗,另外12例术前接受药物治疗后,再给予手术治疗。其中10例全切患者的甲状腺功能恢复正常,4例未能全切除的患者行术后放疗出现垂体功能低下,行激素替代治疗。结论:重视垂体TSH腺瘤的早期诊断,适当进行围手术期处理,选择恰当手术时机,以期为早期发现并给予正确的治疗提供依据。Objective： To analyze clinical characteristics and experiences in the treatment of thyroid-stimulating hormone （TSH）-secreting pituitary adenoma. Methods： To summarize the diagnosis, treatment and prognosis of 14 cases of pituitary thyrotropin （TSH） tumor in the Department of Neurosurgery, 251 Hospital of China People＇s Liberation Army （PEA） from January 2006 to February 2014. Results： Of 14 patients, two received direct surgical treatment and 12 received drug treatment before surgery. Thyroid function fully recovered in 10 patients who underwent total tumor resection. Four patients, for whom resections failed, were treated with hormone replacement therapy after radiotherapy. Conclusions： It is important to diagnose TSH-secreting pituitary adenoma early, perform proper perioperative management, and choose the right operative time after early diagnosis and select correct treatment.

关 键 词：垂体促甲状腺素 垂体瘤 微腺瘤 治疗 

分 类 号：R736.4[医药卫生—肿瘤]