基于隐结构模型和频繁项集的数据挖掘方法探讨慢性萎缩性胃炎的辨证取穴规律  

Acupoint selection pattern of chronic atrophic gastritis based on data mining methods of latent structure model and frequency item set

作　　者：刘余 龚后武 刘家庆 张泓[1] LIU Yu;GONG Houwu;LIU Jiaqing;ZHANG Hong(College of Acupuncture-Moxibustion and Tuina, Hunan University of CM, Changsha 410208, China;DHC Software Co. Ltd)

机构地区：[1]湖南中医药大学针灸推拿学院,长沙410208 [2]东华软件研究院长沙分院

出　　处：《中国针灸》2018年第6期667-671,共5页Chinese Acupuncture & Moxibustion

基　　金：湖南省教育厅资助项目:16 C 1230

摘　　要：目的:探讨中医对慢性萎缩性胃炎的辨证取穴规律,为临床治疗慢性萎缩性胃炎提供参考。方法:计算机检索中国期刊全文数据库(CNKI)、中国生物医学文献数据库(CBM)、Pub Med等数据库中建库至2016年9月5日针刺辨证取穴论治慢性萎缩性胃炎的相关文献,提取症状、取穴处方信息构建慢性萎缩性胃炎医案数据库,采用隐结构模型、频繁项集等数据挖掘方法,分析针刺治疗慢性萎缩性胃炎的辨证取穴规律。结果:初检索出文献42篇,经筛选,共计纳入文献32篇,涉及604例病历资料。数据挖掘分析得出医案中共涉及215项症状,高频症状16项,包括胃脘疼痛、胃脘胀满、嗳气呃逆等,建立慢性萎缩性胃炎证候隐结构模型。统计出高频取穴处方,共涉及52个腧穴,其中高频取穴包括足三里、中脘、内关、胃俞等;挖掘出症状-腧穴频繁项集5项,包括胃脘疼痛+胃脘胀满+足三里+中脘等;症状-证型-腧穴频繁项集6项,其中包括胃脘胀痛+口干+大便干+胃阴不足证+三阴交。结论:针刺治疗慢性萎缩性胃炎多以足三里、中脘、内关为主穴,配穴依据临床情况辨证取穴,此可为临床治疗慢性萎缩性胃炎提供参考。Objective To explore the acupoint selection pattern of chronic atrophic gastritis and provide reference for clinical treatment of chronic atrophic gastritis. Methods The literature regarding acupuncture for chronic atrophic gastritis published before September 5 th of 2016 was searched in the databases of CNKI, CBM, Pub Med, etc. The information of symptoms and acupoint selection was extracted to establish medical database of chronic atrophic gastritis. The data mining methods of latent structure model and frequency item set were applied to analyze the acupoint selection pattern of chronic atrophic gastritis. Results A total of 42 papers were collected in preliminary screening, and 32 papers were included, involving 604 medical cases. The data mining indicated 215 symptoms were involved in medical cases, including 16 high-frequency symptoms（stomach pain, stomach distension and hiccup, etc.）, and the latent structure model of chronic atrophic gastritis symptoms was established. Fifty-two acupoints were identified, and high-frequency acupoints included Zusanli（ST 36）, Zhongwan（CV 12）, Neiguan（PC 6） and Weishu（BL 21）, etc. Five frequency item sets of symptom-acupoint were identified, including stomach pain＋stomach distension＋Zusanli（ST 36）＋Zhongwan（CV 12）, etc. Six frequency item sets of symptom-syndrome-acupoint were identified, including stomach distension＋dry mouth＋dry defecation＋insufficiency of stomach yin＋Sanyinjiao（SP 6）. Conclusion Acupuncture for chronic atrophic gastritis selected Zusanli（ST 36）, Zhongwan（CV 12） and Neiguan（PC 6） as main acupoints, and selected other acupoints based on clinical symptoms. This could provide reference for clinical treatment of chronic atrophic gastritis.

关 键 词：隐结构模型 频繁项集 慢性萎缩性胃炎 胃脘痛 数据挖掘 辨证取穴规律 

分 类 号：R224.2[医药卫生—中医基础理论]