丹红注射液临床用药合理性分析  

Analysis of Rationality of Clinical Medication of Danhong Injection from 2015 to 2016

作　　者：张明[1] 许丽雯[1] Zhang Ming;Xu Liwen(Pharmacy Department, LongHua Hospital OF Shanghai University of Traditional Chinese Medicine, Shanghai 200032, Chin)

机构地区：[1]上海中医药大学附属龙华医院,上海200032

出　　处：《世界中医药》2018年第4期1001-1005,共5页World Chinese Medicine

基　　金：上海市科委中药现代化专项(09DZ1970300)

摘　　要：目的:观察丹红注射液上市后临床使用的基本情况,并判断其是否合理。方法:选取2015年1月至2016年6月上海中医药大学附属龙华医院收治的使用过丹红注射液的住院患者408例,在不干预患者原有的治疗方案的前提下,从中医"病""证""征"的角度观察丹红注射液在临床中的使用情况。结果:以中医辨证施治为依据,判断其用药是否合理,结果为仅3例患者存在出血倾向,不适用丹红注射液,其余患者用药均合理。结论:各临床科室使用丹红注射液用法基本合理,虽有超说明书用药适应证的情况,但405名患者均有血瘀体征,具备使用丹红注射液活血化瘀治疗的条件。Objective： To observe the basic situation of clinical use of Danhong Injection after the listing and to determine whether it is reasonable. Methods： The patients admitted in our hospital from January 2015 to June 2016 who were received Danhong Injection were selected. The clinical use of Danhong Injection in our hospital was observed from the perspective of TCM＂disease＂＂syndrome＂and ＂sign＂on the premise of not interfering original treatment plan. Results： A total of 408 cases were collected. According to the syndrome differentiation treatment of traditional Chinese medicine,whether drug use was reasonable was determined. The results showed that bleeding tendency only existed in 3 cases,who did not apply to Danhong Injection. The treatment of rest patients was reasonable. Conclusion： The clinical departments used Danhong Injection in reasonable way. Although medicine indications exceed manual at some situation,but the 405 patients all had blood stasis symptoms. Those patients had the conditions in the treatment of using Danhong Injection.

关 键 词：丹红注射液 中医辨证论治 合理用药 上市后再评价 出血倾向 药物不良反应 溶媒配伍 

分 类 号：R285.6[医药卫生—中药学]