脑宁胶囊的质量标准研究  

Study on the Quality Standard of Naoning Capsule

作　　者：马春梅[1] 王娟[1] Ma Chunmei;Wang Juan(Xuzhou Vocationgal College of Bioengineering, Xuzhou 221006, J iangSu ,China)

机构地区：[1]徐州生物工程职业技术学院生物工程系,江苏徐州221006

出　　处：《四川化工》2018年第3期32-35,共4页Sichuan Chemical Industry

基　　金：徐州生物工程职业技术学院科技计划项目(2015KY01)

摘　　要：[目的]:建立脑宁胶囊的质量控制标准。[方法]:采用TLC法对制剂的赤芍进行鉴别,采用HPLC法以芍药苷为指标性成分,对其进行含量测定。[结果]:TLC法鉴别赤芍斑点分离效果较好,无阴性干扰。每粒胶囊的芍药苷含量不低于8.22mg/粒。[结论]:该方法专属性强、重现性好,可用于脑宁胶囊制剂的质量控制。[Objective]：To establish the quality control standard in Naoning capsule.[Methods]：TLC was used for identification of Red peony root in the Preparation,the content of paeoniflorin was determined by HPLC and Using paeoniflorin as index component.[Results]：The separation effect of red peony spots was better by TLC,and there was no negative interference.The content of paeoniflorin in each capsule was not lower than that in 8.22 mg/granules.[Conclusion]：The method is specific and reproducible,and it can be used for the quality control of Naoning capsule.

关 键 词：脑宁胶囊 质量标准 芍药苷 

分 类 号：TQ460.72[医药卫生—药物分析学]