129例肺癌患者病理组织类型与支气管镜下表现及临床特征的关系分析  

Correlation analysis of the pathological type with bronchoscopic signs and clinical features of 129 patients with lung cancer

作　　者：王艺[1] 陈旭昕[2] 徐剑铖[3] 李秋梅[1] Wang Yi1, Chen Xunxin2, Xu Jiancheng3, Li Qiumei1(1Department ofRespiratoray Medicine, the Sixth People′ s Hospital of Ji ＇nan City Affiliated to Jining Medical College, Jinan250200, China; 2Department of Respiratory Medicine, Nary General Hospital of PLA, Beijing 100037, China;3Institute of Respiration Diseases, Xinqiao Hospital Affiliated to Third Military Medical University, Chongqing400037, Chin)

机构地区：[1]济宁医学院附属济南市第六人民医院呼吸内科,济南250200 [2]中国人民解放军海军总医院呼吸内科,北京100037 [3]第三军医大学新桥医院全军呼吸内科研究所,重庆400037

出　　处：《中华肺部疾病杂志（电子版）》2018年第2期190-194,共5页Chinese Journal of Lung Diseases(Electronic Edition)

摘　　要：目的探讨肺癌患者病理组织类型与电子支气管镜下表现和临床特征的关系。方法对经电子支气管镜检查的129例肺癌患者的性别、年龄、病变部位、病理类型、镜下改变进行回顾性分析和统计学处理。结果 (1)肺癌的病变部位右肺多于左肺,左肺上叶多于左肺下叶,右肺上、中、下三叶无差异;(2)男性患者以鳞癌最多,女性患者以腺癌最多,两组对比差异有统计学意义(P<0.05);(3)青年组以小细胞癌最多,腺癌次之,中年组及老年组以腺癌最多,鳞癌次之,青年组与老年组对比差异有统计学意义(P<0.05);(4)鳞癌多表现为管腔内增生,腺癌多表现为管壁浸润及管腔内增生,小细胞癌多表现为管壁浸润及管腔外压狭窄,电子支气管镜下特征与肺癌病理类型相关性有统计学意义(P<0.05);(5)刷检的阳性率是63.6%,钳检的阳性率是81.3%,两种方法对比差异有统计学意义(P<0.01)。结论肺癌病理组织类型与支气管镜下表现和临床特征密切相关。Objective To investigate the relationship of the pathological type with bronchoscopic signs and clinical features in patients with lung cancer. Methods 129 patients with lung cancer were checked by electronic bronchoscope, and the data of their gender, age, and site of lesions, endoscopic signs and histological type were retrospectively analyzed. Results The location of lung carcinoma was more likely in the right lung than the left lung. The upper lobe was more often invaded than the lower lobe in the left lung,but there was no difference between the three lobes in the right lung. It was obviously different in the distribution of lung cancer histopathology between male and female patients（P〈0.05）,in which squamous cell carcinoma was dominant in male patients,but adenocarcinoma was often found in female patients. The most common cancer type in the young patients was small cell carcinoma,followed by adenocarcinoma; while adenocarcinoma was frequently seen in middle-aged and older patients,followed by squamous cell carcinoma; the difference between young group and old group was significantly different（P〈0. 05）. The endoscopic signs of squamous cell carcinoma were mainly proliferation in the trachea or bronchus; the adenocarcinoma mainly showed infiltration and proliferation,and the small cell carcinoma mainly showed infiltration and oppressed stenosis of the trachea or bronchus. The features under the bronchoscope were related with the histology types（P〈0.05）. The positive rate of brush biopsy was 63.6%.The positive rate of clamp examination was 81.3%.There was significant difference between the two methods（P〈0.01）.ConclusionThe pathological type is closely related with bronchoscopic signs and clinical features in patients with lung cancer.

关 键 词：电子支气管镜 支气管肺癌 病理分型 卡方检验 

分 类 号：R734.2[医药卫生—肿瘤]