急性脑梗死病灶与颈动脉硬化斑块性质相关性的超声研究  

Ultrasonic study on the correlation between the foci of acute cerebral infarction and the properties of carotid atherosclerotic plaque

作　　者：刘建英[1] 陈立伟[2] 沈新天[1] LIU Jianying;CHEN Liwei;SHEN Xintian(Department of Neurology;Ultrasound Room,Tianjin Yellow River Hospital,Tianjin 300110,China)

机构地区：[1]天津市黄河医院神经内科,天津300110 [2]天津市黄河医院彩超室,天津300110

出　　处：《中国实用神经疾病杂志》2018年第10期1045-1049,共5页Chinese Journal of Practical Nervous Diseases

摘　　要：目的采用多普勒超声成像探讨急性脑梗死病灶与颈动脉硬化斑块性质的相关性。方法以天津市黄河医院2015-01—2017-01收治的急性脑梗死患者200例为研究对象,按脑梗死病灶大小分为小面积梗死组(n=54)、中等面积梗死组(n=77)、大面积梗死组(n=69),采用多普勒超声成像技术对3组颈动脉硬化斑块进行检查,对比颈动脉硬化斑块内中膜厚度、斑块大小、管腔直径、斑块部位及分型、狭窄程度、血流动力学等指标。采用Spearman检验对急性脑梗死病灶与颈动脉硬化斑块性质进行相关性分析。结果 3组颈动脉硬化斑块内中膜厚度、管腔直径、斑块部位、斑块分型比较差异无统计学意义(P>0.05),而斑块大小、狭窄程度差异有统计学意义(P>0.05)。3组舒张末期流速(EDV)、阻力指数(RI)比较差异无统计学意义(P>0.05),而峰值流速(SPV)和搏动指数(PI)差异有统计学意义(P<0.05)。经Spearman检验,急性脑梗死病灶大小与颈动脉硬化斑块大小、颈动脉狭窄程度、SPV、PI呈明显正相关。结论急性脑梗死与颈动脉硬化斑块有密切关联,且病灶大小与颈动脉硬化斑块大小、狭窄程度、SPV、PI呈正相关,对不同病情程度的急性脑梗死患者的病情判断及诊治有重要指导意义。Objective To investigate the correlation between lesion size and carotid atherosclerotic plaques in patients with acute cerebral infarction. Methods Totally 200 cases of acute cerebral infarction patients from January 2015 to January 2017 in Tianjin Yellow River Hospital were selected as the research objects,and were divided into small area infarction group （ n =54）,medium infarction group （ n =77）,large area infarction group （ n =69）.Using the Doppler ultrasondto examine the carotid atherosclerosis plaque in the three groups,intima media thickness,plaque size,lumen diameter,plaque location and type,degree of stenosis and hemodynamic indexes were compared.Using the Spearman test to analyze the correlation between the size oflesion and the nature ofcarotid atherosclerotic plaque in the patients with acute cerebral infarction. Results There were no significant differencesamong the three groups in the thickness of carotid atherosclerotic plaques,the diameter of lumen,the location of plaques,and the type of plaque.There were no significant differencesamong the three groups （ P 〉0.05）,but there were statistically significant differencesinplaque size and stenosis degree among three groups（ P 〈0.05）.There were no significant differences in the end diastolic velocity （EDV） and the resistance word number （RI） among the three groups （ P 〉0.05）,while the peak flow velocity （SPV） and pulsatility index （PI） in the three groups were statistical significance （ P 〈0.05）.By Spearman test,the size of the lesions in acute cerebral infarction was positively correlated with the size of carotid atherosclerotic plaques,the degree of carotid artery stenosis,SPV and PI. Conclusion The occurrence of acute cerebral infarction in patients with carotid artery atherosclerosis and cerebral infarction is closely related.Lesion size is positively correlated with carotid plaque size,degree of stenosis,SPV and PI,which has important guiding significance in diagnosis and treatment of different

关 键 词：急性脑梗死 病灶大小 颈动脉硬化斑块 相关性分析 多普勒超声 

分 类 号：R743.33[医药卫生—神经病学与精神病学]