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作 者:吉翔 于建平 石鑫 王朝阳[1] 李洪涛[1] 韩晓鹏[1] 刘宏斌[1] Ji Xiang;Yu Jianping;Shi Xin;Wang Zhaoyang;Li Hongtao;Han Xiaopeng;Liu Hongbin(Lanzhou General Hospital of Chinese People's Liberation Army (PLA),Gansu Lanzhou 730050,China)
机构地区:[1]中国人民解放军兰州总医院,甘肃兰州730050
出 处:《现代肿瘤医学》2018年第11期1757-1759,共3页Journal of Modern Oncology
基 金:甘肃省自然科学基金(编号:1506RJZA309)
摘 要:目的:报道1例少见的脾脏窦岸细胞血管瘤(littoral cell angioma,LCA),以提高临床医师对该疾病的认识。方法:对1例LCA的临床、病理特征、免疫组化及术后随访情况进行分析并复习文献。结果:LCA具有内皮标记如CD31以及组织细胞标记如CD68双重分化的特征。结论:LCA是脾脏的良性肿瘤,病理上易与窦岸细胞血管内皮瘤和窦岸细胞血管肉瘤等混淆,诊断依靠病理组织学表现及免疫组化特点。行脾切除术可治愈,预后良好。Objective:To report 1 case of littoral cell angioma( LCA) of spleen.Methods:The clinical manifestations,pathology,expression of immunohistochemistry,and the follow up of 1 case of LCA was analyzed,and the related literature was reviewed.Results:Immunostaining revealed there were the characteristics of the double differentiation of endothelial markers such as CD31 and tissue cell markers such as CD68.Conclusion:LCA is a benign lesion of spleen which had a remarkably characteristic appearance.The pathology is easy to confuse with sinus vascular endothelial cells and tumor bank littoral cell angiosarcoma etc.The diagnosis counts on the pathologic and inmunohistochemical findings.It could be cured by splenectomy with a favourable prognosis.
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