不同年龄段宫颈癌患者的病理特点及预后分析  

Pathological characteristics and prognosis of cervical cancer in different age groups

作　　者：孙晓东[1] 刘敏[1] 鲍慧 年亮 段伟[1] 张璐[1] 刘宁宁[1] 胡海峰[1] 乔健[1] 康婷[1] Sun Xiaodong;Liu Min;Bao Hui;Nian Liang;Duan Wei;Zhang Lu;Liu Ningning;Hu Haifeng;Qiao Jian;Kang Ting(Department of Oncology,Affiliated Hospital of Yan＇an University,Shaanxi Yan＇an 716000,China.)

机构地区：[1]延安大学附属医院肿瘤科,陕西延安716000

出　　处：《现代肿瘤医学》2018年第11期1766-1769,共4页Journal of Modern Oncology

基　　金：延安大学附院院内科研项目(编号:2012YDFY-Y310)

摘　　要：目的:研究影响宫颈癌患者预后的相关因素,不同年龄段患者的病理分期特点与差异,为今后的治疗提供可靠依据。方法:选取2012年1月至2013年1月我院收治的100例宫颈癌患者,按照年龄段的不同分为对照组(年龄<35岁)与观察组(年龄>35)岁,每组各50例。对所有患者的临床资料进行回顾性分析,总结患者的临床特征及预后情况。结果:中青年宫颈癌患者的3年生存率显著低于中老年患者(P<0.01),且2年内复发率明显高于中老年患者(P<0.01),两组患者在初次性生活史、避孕药的使用、HPV检查结果阳性、肿瘤分期、大小、病理类型等比较上,差异有统计学意义(P<0.01)。结论:对于中青年患者来说,定期进行宫颈癌筛查,不仅能尽早发现疾病病变,同时还能尽早治疗,是防止疾病发展和降低死亡率的重要手段。Objective：To study the related factors influencing the prognosis of cervical cancer patients,and to master the characteristics and differences of pathological stages of patients with different ages,so as to provide a reliable basis for future treatment.Methods：100 cases of cervical cancer were selected from January 2012 to 2013 year in January in our hospital as the research object,according to different age groups as control group（ age 35 years） and observation group（ age 35 years）,50 cases in each group.The clinical data of all patients were analyzed retrospectively,and the clinical characteristics and prognosis of the patients were summarized.Results：The 3-year survival rate in young patients with cervical cancer was significantly lower than that in elderly patients（ P〈0.01）,and the recurrence rate within 2 years was significantly higher than that in elderly patients（ P〈0.01）,two groups of patients in the first sexual life history,contraceptive use,HPV positive test result,tumor stage,size and pathologic type comparison of（ P〈0.01）,the difference was statistically significant.Conclusion：For young and middle-aged patients,regular cervical cancer screening,not only can be found as early as possible,but also early treatment,is an important means to prevent the development of the disease and reduce mortality.

关 键 词：宫颈癌 临床特征 病理特点 年龄段 分期 

分 类 号：R737.33[医药卫生—肿瘤]