抑郁症和肠道微生态的关联性研究(综述)  

A review of association between depression and intestinal microecology

作　　者：郑少君 王志仁[2] 王永前[1] 张琪[2] 赵文暄 李娟[2] 杨甫德[2] ZHENG Shaojun;WANG Zhiren;WANG Yongqian;ZHANG Qi;ZHAO Wenxuan;LI Juan;YANG Fude(l Inner Mongolia Medical University, Hohhot 010110, China;Beijing Huilongguan Hospital, Peking University Huilongguan Clinical Medical School, Beijing 100096, China)

机构地区：[1]内蒙古医科大学,呼和浩特010110 [2]北京回龙观医院北京大学回龙观临床医学院,北京100096

出　　处：《中国心理卫生杂志》2018年第7期537-541,共5页Chinese Mental Health Journal

基　　金：北京市医院管理局临床医学发展专项(ZYLX201409);北京回龙观医院"龙跃"计划杰出青年基金(2014LYJQ-02);北京市属医院科研培育计划(PX2016010)

摘　　要：肠道内存在人体最大的微生态环境,对于维持人体的健康发挥重要作用。相关研究发现,肠道菌群可能通过肠脑轴(GBA)影响大脑功能与行为,成为探讨和治疗神经精神类疾病的新方向。本文回顾了近年国内外研究成果,发现肠道菌群与抑郁症存在联系,并综述了两者之间的关联性。As the body＇ s largest microecological environment,microbiota plays an important role in human health. It is found that intestinal flora may affect brain function and behavior by changing activation of gut-microbiomebrain axis. This provides a new direction of the exploration of neuropsychiatric disorders ＇ pathogenesis.This paper reviews the recent researches and summarizes the link between depression and intestinal flora.

关 键 词：抑郁症 肠道菌群 脑肠轴 益生菌 综述 

分 类 号：R749.41[医药卫生—神经病学与精神病学]