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作 者:江枫[1] 颜华[1] Jiang Feng;Yan Hua(Department of Ophthalmology, Tianjin Medical University General Hospital, Tianjin 300052, Chin)
出 处:《中华眼底病杂志》2018年第4期412-415,共4页Chinese Journal of Ocular Fundus Diseases
摘 要:视网膜小胶质细胞是视网膜的免疫细胞,参与视网膜免疫反应。近年发现小胶质细胞在糖尿病视网膜病变(DR)的发病过程中扮演重要角色,同时参与DR神经变性及微血管病变的病理过程。了解视网膜小胶质细胞的功能及其在DR发病及治疗机制中的作用,通过精准调控小胶质细胞可能为DR的治疗开辟新途径。Retinal microglial cells are immune cells of the retina and participate in the retinal immune response. In recent years, it has been found that microglia plays an important role in the pathogenesis of diabetic retinopathy (DR), and is involved in the pathological process of neurodegeneration and microvascular disease in DR. Understanding the function of retinal microglial cells and their role in the pathogenesis DR may open up new avenues for the treatment of DR through the precise regulation of microglia
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