中药治疗与传统认知训练联合虚拟技术对阿尔兹海默病患者的疗效评价  

The effect of combination of traditional Chinese medicine treatment, traditional cognitive training and virtual technique treatment on the cognitiive function in patients with Alzheimer's disease

作　　者：杨伟[1] 王红[1] 陈卓铭[1] 牟志伟[1] 卢建亮[1] 徐晓萍[1,2] 韩晶 YANG Wei;WANG Hong;CHEN Zhuoming(The First Affiliated Hospital of Jinan University, Guangzhou, 510630)

机构地区：[1]暨南大学附属第一医院康复医学科,广州510630 [2]暨南大学社区卫生服务中心 [3]新疆维吾尔自治区人民医院

出　　处：《中国康复医学杂志》2018年第7期783-788,共6页Chinese Journal of Rehabilitation Medicine

基　　金：广州市科技计划项目重大民生专项(2012Y2-00023);广东省哲学社会科学"十二五"规划2012年度学科共建项目(GD12XYJ19)

摘　　要：目的:运用中药辨证治疗与传统认知训练,联合虚拟现实情景互动技术,对轻度阿尔兹海默病患者进行早期认知干预,观察其疗效。方法:将符合纳入条件的68例患者,随机分为对照组(n=34例)和治疗组(n=34例),均予每周6天、连续6个月的治疗,对照组给予中药辨证论治结合传统认知训练,治疗组在对照组的基础上联合虚拟现实情景互动(Anokan-VR)技术治疗。采用简易智能精神状态检查量表(MMSE),功能独立性评定(FIM)量表、韦氏记忆测验修订版(WMS,1999)对两组患者治疗前及治疗后的疗效进行评价比较。结果:治疗前后两组的MMSE评分、FIM评分、WMS评分,均有显著性变化(P<0.05);且治疗后治疗组的效果明显优于对照组(P<0.05或P<0.01)。结论:传统认知训练结合中药辨证论治,可改善轻度阿尔兹海默病患者的认知功能,在此基础上联合虚拟现实情景互动技术,疗效更佳。Objective： To observe the effect of Combining traditional Chinese medicine treatment, traditional cognitive training and virtual technique treatment on the cognitiive function of patients with Alzheimer＇s disease. Method： A total of 68 patients were recruited and randomly divided into control group （n=34） and treatment group （n=34）. The treatment group received a combination of traditional Chinese medicine treatment, traditional cognitive training and virtual technique treatment, while the control group received only a combination of traditional Chinese medicine treatment and traditional cognitive training. The time of treatment in two groups were both 6 months （6 days per week）. MMSE, FIM, and WMS were used to evaluate the therapeutic effect. Result： The MMSE score, FIM score and WMS scores were significantly different before and after treatment for two groups （P〈0.05）. The improvement of treatment group was significantly better than the control group （P〈0.05 or P〈0.01）. Conclusion： Combination of traditional Chinese medicine treatment, traditional cognitive training can significantly improve cognitive function of patients with Alzheimer＇s disease. Combining Anokan-VR on above treatments can get much better effect.

关 键 词：阿尔兹海默病 虚拟技术 认知训练 中药治疗 

分 类 号：R749.1[医药卫生—神经病学与精神病学] R242[医药卫生—临床医学]