临床病例讨论 第464例——急性白血病，突发抽搐伴昏迷  

The 464th case： sudden convulsion and coma in a patient with acute leukemia

作　　者：刘扬[1] 黄晓军[1] 江浩[1] 朱宇[2] 周翔海[2] 宫立众 Liu Yang;Huang Xiaojun;Jiang Hao;Zhu Yu;Zhou Xianghai;Gong Lizhong(Peking University People＇s Hospital,Peking University Institute of Hematology,Beijing 100044,China)

机构地区：[1]北京大学人民医院血液科北京大学血液病研究所,100044 [2]北京大学人民医院内分泌科,100044

出　　处：《中华内科杂志》2018年第7期539-541,共3页Chinese Journal of Internal Medicine

摘　　要：患者女性，46岁。因“间断牙龈肿痛伴出血1周”人院，诊断急性混合细胞白血病。给予诱导化疗效果不佳，第2次化疗过程中突发抽搐、意识不清，转入重症监护病房经积极治疗控制后又不断反复。最终诊断：继发性。肾上腺皮质功能不全，肾上腺危象，顽固性低钠血症，脑水肿。A 46-year-old female patient was diagnosed as mixed phenotype acute leukemia with chief complaints of intermittent gingival swelling and bleeding for 1 week. The induction chemotherapy was not effective. During the second course chemotherapy, the patient had sudden convulsion and coma. She was transferred to the intensive care unit with worsened condition after transient improvement. Her final diagnosis was secondary adrenoeortical insufficiency, adrenal crisis, intractable hyponatremia and cerebral edema.

关 键 词：急性混合细胞白血病 意识障碍 

分 类 号：R733.71[医药卫生—肿瘤]