CA125和CEA在卵巢恶性肿瘤诊断中的作用  

EFFECT OF CA125 AND CEA IN DIAGNOSIS OF PREOPERATIVE OVARIAN CANCER

作　　者：杨晓花[1] 李瑞民[1] 徐大为[1] 郑建军[1] 张玉娟[2] 刘静[2] 李瑞芳[2] 

机构地区：[1]承德医学院,河北承德067000 [2]承德医学院附属医院

出　　处：《承德医学院学报》2002年第3期187-189,共3页Journal of Chengde Medical University

摘　　要：目的 :应用 CA12 5及 CEA抗原联合检测对卵巢肿物的良、恶性进行回顾性评价 ,探讨卵巢恶性肿瘤的早期诊断方法。方法 :共收治 2 96例卵巢肿瘤病人 ,其中 ,16 4例是良性肿瘤、132例为恶性肿瘤患者。分别以病人术前 CA12 5水平、CEA值和超声检查结果作为对卵巢肿瘤良、恶性程度预测的指标 ,比较其敏感性、特异性和阳性预测值。结果 :CA12 5和 CEA联合检测 ,其敏感性、特异性、阳性预测值均高于单独 CA12 5或 CEA检测 ,相对阳性率可提高至 93.2 0 %。结论 :卵巢肿瘤病人血清 CA12 5和 CEA联合检测指标确定肿瘤的良、恶性程度较其他方法更为准确、可靠 ,具有重要的临床意义。Objective:To discriminate benign from malignant pelvic mass based on serum CA125 and CEA levels.Methods:Two hundred and ninety six women with ovarian cancer were studied.The sensitivity,specificity and positive predictive value of serum CA125 and CEA level,ultrasound findings were used to diagnosis benign or malignant of ovarian cancer.Results:The sensitivity,specificity and positive predictive value of serum CA125 combined with CEA detection were more accurate than individual test in diagnosis cancer,positive rate reach to 93.20%.Conclusions:This strategy could correctly discriminate between benign and malignant pelvic mass.It can be easily wed to clinical practice to evaluate patients with ovarian cancer.

关 键 词：CA125 卵巢恶性肿瘤 诊断 卵巢肿瘤 

分 类 号：R737.31[医药卫生—肿瘤]