原发性肝癌患者应用无血切肝技术治疗的效果及对生存率的影响  

Effect of bloodless liver resection in patients with primary liver cancer and its influence on survival rate

作　　者：许马川 梁文杰 陈晚妹 XU Machuan;LIANG Wenjie;CHEN Wanmei(Department of General Surgery,the People＇s Hospital of Yangjiang City,Yangjiang 529500,Chin)

机构地区：[1]广东省阳江市人民医院普通外科,广东阳江529500

出　　处：《中国医药科学》2018年第14期219-222,共4页China Medicine And Pharmacy

摘　　要：目的探究原发性肝癌患者应用无血切肝技术治疗的效果及对生存率的影响。方法选取2016年7月~2017年4月期间我院收治的原发性肝癌患者60例作为研究对象,按照随机分组方法分为对照组和实验组,一组是常规三维适形放疗技术进行手术,另一组是用无血切肝技术进行手术,其中,对照组30例,采用常规三维适形放疗技术,而实验组30例,采用的是无血切肝技术,观察比较两组患者的生存率、治疗效果、术中出血量等指标。结果两组在术中出血量、输血量、术后住院天数等指标上差异有统计学意义(P<0.05),实验组总有效率为93.33%,对照组为76.67%,差异有统计学意义(P<0.05);两组患者接受不同的治疗方法后,临床指标均得到了显著的改善,但实验组的改善情况显著优于对照组(P<0.05),对照组1年生存率70%(21/30),2年生存率60%(18/30),3年生存率30%(9/30)。实验组1年生存率90%(27/30),2年生存率80%(24/30),3年生存率56.67%(17/30),差异有统计学意义(P<0.05)。结论无血切肝技术治疗原发性肝癌,可减少术中出血量,缩短住院天数,而且有效提高患者生存率,值得推广。Objective To explore the effect of bloodless liver resection in patients with primary liver cancer and its influence on survival rate. Methods Sixty cases of primary liver cancer patients who treated in our hospital from July 2016 to April 2017 were selected as an object of study and were randomly divided into control group and experimental group according to the surgical method. Thirty patients in the control group were treated with conventional 3D conformal radiotherapy technology, while the experimental group（30 cases） was given bloodless liver resection. The survival rate, the effect of treatment, intraoperative blood loss and other indicators of the two groups were observed. Results There were significant differences in intraoperative blood loss, blood transfusion volume, postoperative hospital days and other indicators between the two groups（P 〈0.05）. The total effective rate was 93.33% in the experimental group and 76.67% in the control group, the difference was statistically significant（P 〈0.05）. After received different treatment methods, the clinical indicators of two groups were significantly improved, but the improvement in the experimental group was significantly better than that in control group（P 〈0.05）. In the control group, the 1-year survival rate was 70%（21/30）, the 2-year survival rate was 60%（18/30）, and the 3-year survival rate was 30%（9/30）. In the experimental group, the 1-year survival rate of was 90%（27/30）, the 2-year survival rate was 80%（24/30）, and the 3-year survival rate was 56.67%（17/30）, the difference of two groups was statistically significant（P 〈0.05）. Conclusion Bloodless liver resection can reduce intraoperative bleeding, shorten hospitalization days, and effectively improve the survival rate of patients with primary liver cancer, it is worth promoting.

关 键 词：原发性肝癌 恶性肿瘤 手术治疗 无血切肝技术 

分 类 号：R735.7[医药卫生—肿瘤]