屈光不正儿童后极部视网膜厚度及视盘周围神经纤维层厚度的观察  

Posterior pole retinal thickness and retinal nerve fiber layer thickness in children with refractive error by SD-OCT

作　　者：李翊 黄江[2] 肖建江 史慧民 周娴 曹霞 周强 王庆平 Yi Li;Jiang Huang;Jian-Jiang Xiao;Hui-Min Shi;Xian Zhou;Xia Cao;Qiang Zhou;Qing- Ping Wang(Department of Ophthahnology,North Branch of Huashan Hospital,Fudan University,Shanghai 201907,China;Department of Ophthahnology,the Second Affiliated Hospital of Soochow University,Suzhou 215004,Jiangsu Province,China)

机构地区：[1]复旦大学附属华山医院北院眼科,中国上海市201907 [2]苏州大学附属第二医院眼科,中国江苏省苏州市215004

出　　处：《国际眼科杂志》2018年第8期1499-1502,共4页International Eye Science

基　　金：上海申康医院发展中心临床科技创新项目(No.SHDC12015907)~~

摘　　要：目的:利用频域光学相干断层扫描仪(SD-OCT)对屈光不正儿童后极部视网膜厚度及视网膜神经纤维层(retinal nerve fiber layer,RNFL)厚度进行测量,探讨年龄、屈光度与视网膜厚度之间的相关性。方法:收集2016-02/2017-02在复旦大学附属华山北院眼科门诊就诊的5～15岁屈光不正儿童96例192眼,应用SD-OCT设备对受检者视盘周围RNFL厚度和后极部视网膜厚度(posterior pole retinal thickness,PPRT),包括后极部20°范围内以视盘和黄斑连线为界,分为上方、下方、平均PPRT及距黄斑中心凹1mm视网膜厚度进行检测,并分析年龄、屈光度与PPRT及RNFL厚度的相关性。结果:SD-OCT检查示,本组病例距黄斑中心凹1mm视网膜厚度为252.72±13.87μm,平均PPRT为294.02±8.70μm,上方PPRT为294.53±9.11μm,下方PPRT为293.53±9.50μm,RNFL厚度为105.75±10.60μm。年龄与距黄斑中心凹1mm视网膜厚度呈正相关,屈光度与PPRT及RNFL厚度均呈正相关。结论:SD-OCT能够准确测量儿童后极部视网膜厚度,年龄、屈光度与视网膜厚度及RNFL厚度具有相关性。AIM： To measure the posterior pole retinal thickness and retinal nerve fiber layer（ RNFL） thickness using the Heidelberg spectral domain optical coherence（ SD-OCT）, and explore the correlation between age,refraction diopter and retinal thickness.METHODS： A total of 192 eyes of 96 healthy children with the age from 5 to 15 years old were examined by routine ophthalmic examinations. The SD-OCT of Spectralis Heidelberg was used to examine the thickness of the posterior retina and optic nerve fibers of the subjects within 20° and this district was divided to superior and inferior by the line collecting optic disc and macula. The detection was taken within the area of 1 mm away the macular fovea. The correlation between age,refraction diopter and change of retinal morphology were analyzed.RESULTS： The average thickness of the retina around 1 mm area from the fovea was 252. 72 ± 13. 87μm,the mean posterior pole retinal thickness（ PPRT） was 294. 02±8. 70μm,the superior PPRT was 294. 53±9. 11μm,the inferior PPRT was 293. 53±9. 50μm,and the average RNFL thickness was 105. 75 ± 10. 60μm. There were positive correlation between age and PPRT,and positive correlation between diopter,PPRT and RNFL thickness.CONCLUSION： SD-OCT can accurately measure the thickness of children＇s retina,and there is a correlation between age,refractive diopter and retinal thickness.

关 键 词：频域光相干断层扫描 儿童 后极部视网膜厚度 神经纤维层厚度 

分 类 号：R774.1[医药卫生—眼科]