糖尿病肾病中医证候的现代研究  

Modern Study on Traditional Chinese Medicine Syndromes of Diabetic Nephropathy

作　　者：王倩 严美花[1] 李平[1] Wang Qian;Yan Meihua;Li Ping(Institute of Clinical Medicine,China-Japan Friendship Hospital,Beijing 100029,China;Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]中日友好医院临床医学研究所,北京100029 [2]北京中医药大学,北京100029

出　　处：《世界中医药》2018年第6期1320-1324,1331,共6页World Chinese Medicine

基　　金：国际(地区)合作与交流项目(81620108031);国际科技合作项目(2011DFA31860)

摘　　要：糖尿病肾病是糖尿病重要的微血管并发症,目前尚无令人满意的西医治疗方法。中医中药在糖尿病肾病的治疗上具有一定的优势和特色。中医证候是辨证论治的核心,是中医学对疾病的定位及定性,决策了疾病的治疗方案及用药配伍方法,是现代医学探索中医学、联合中西医的关键切入点之一。运用现代医学的研究技术与手段使糖尿病肾病的中医证候逐步实现客观化及量化,对中医药在糖尿病肾病的认识、诊治及提高疗效中至关重要,更有利于推进中医药发展并促进中西医结合。据此,特结合近年来有关糖尿病肾病中医证候的研究概况,依次从其现代研究方法及证候分布情况、证型与理化指标的相关性,以及代谢组学方法在中医证候研究中的应用3方面展开论述,以期为糖尿病肾病的现代医学研究及临床诊疗提供新思路。Diabetic nephropathy is an important microvascular complication of diabetes mellitus,which is still no satisfactory treatment by western medicine at present.Traditional Chinese Medicine（ TCM） has some advantages and characteristics in the treatment of diabetic nephropathy.TCM syndrome is the core of syndrome differentiation and treatment,and it is the localization and qualitative analysis of diseases in TCM,the decision-making of disease treatment program,and the compatibility method of medications.It is also one of the key breakthrough points for modern medicine to explore TCM and to combine Chinese and Western medicine.Using modern medical study technologies and means to make TCM syndromes of diabetic nephropathy gradually achieve objectification and quantification,it is very important for TCM to recognize,diagnose and improve the curative effect of diabetic nephropathy,and is more conducive to promote the development of TCM and the integration of Chinese and Western medicine.Therefore,combining with recent studies on the TCM syndrome of diabetic nephropathy,this paper started from three aspects of its syndrome,which were the modern research methods and the distribution of syndrome,the correlation between syndromes and the index of western medicine,and the application of metabolomics in TCM syndrome research,in order to provide new ideas for modern medical study and clinical diagnosis and treatment of diabetic nephropathy.

关 键 词：糖尿病肾病 中医药 证候 证型 研究方法 理化指标 系统生物学 代谢组学 

分 类 号：R587.1[医药卫生—内分泌] R2-03[医药卫生—内科学]