电视胸腔镜与传统开胸肺叶切除术治疗Ⅰ～Ⅱ期非小细胞肺癌的效果及对CRP水平的影响  

Clinical effect of video-assisted thoracoscopic and conventional thoracotomy lobectomy in the treatment of stage Ⅰ-Ⅱ non-small cell lung cancer and its influence on CRP level

作　　者：石鹏飞 王伟峰 SHI Peng-fei;WANG Wei-feng＊(the First People＇s Hospital of Xianyang City,Xianyang 712000,China)

机构地区：[1]陕西省咸阳市第一人民医院,陕西咸阳712000

出　　处：《临床医学研究与实践》2018年第22期42-43,共2页Clinical Research and Practice

摘　　要：目的探讨电视胸腔镜与传统开胸肺叶切除术治疗Ⅰ~Ⅱ期非小细胞肺癌的效果及对患者CRP水平的影响。方法选择我院2014年3月至2016年12月收治的Ⅰ~Ⅱ期非小细胞肺癌患者94例作为研究对象,随机分为对照组和观察组,每组47例。对照组给予传统开腹肺叶切除术治疗,观察组给予电视胸腔镜肺叶切除术。比较两组患者治疗前、后CRP水平、并发症及预后情况。结果治疗后1、3 d,两组患者的CRP水平较治疗前明显升高,但观察组明显低于对照组(P<0.05)。观察组心律失常、支气管胸膜瘘和肺部感染发生率均低于对照组(P<0.05)。观察组术后1年生存率为76.60%,高于对照组的59.57%,但差异无统计学意义(P>0.05)。结论Ⅰ~Ⅱ期非小细胞肺癌患者行电视胸腔镜肺叶切除术治疗临床效果理想,值得推广和应用。Objective To investigate the clinical effect of video-assisted thoracoscopic and conventional thoracotomylobectomy in the treatment of stageⅠ-Ⅱ non-small cell lung cancer and its influence on CRP level. Methods FromMarch 2014 to December 2016, 94 patients with stageⅠ-Ⅱ non-small cell lung cancer admitted in our hospital wereselected as the study objects. All the patients were randomly divided into control group and observation group, with 47patients in each group. The patients in the control group underwent conventional thoracotomy lobectomy, and patients inthe observation group were treated with video-assisted thoracoscopic lobectomy. The CRP levels before and after treatment,complications and prognosis of the two groups were compared. Results At 1 and3d after treatment, the CRP levels in thetwo groups increased than those before treatment, but those in the observation group were lower than the control group （P〈0.05）. The incidences of arrhythmia, bronchopleural fistula and pulmonary infection in the observation group were lowerthan those in the control group （P〈0.05）. The postoperative 1-year survival rate in the observation group was 76.60%,which higher than 59.57% in the control group, with no significant difference between the two groups（P〉0.05）. ConclusionFor stage Ⅰ-Ⅱ non-small cell lung cancer patients, video -assisted thoracoscopic lobectomy has satisfactory clinicaleffect, which is worthy of clinical application and promotion.

关 键 词：Ⅰ-Ⅱ期非小细胞肺癌 传统开胸肺叶切除术 电视胸腔镜肺叶切除术 CRP 

分 类 号：R734.2[医药卫生—肿瘤]